Description

2-(Hydroxymethyl)-12-Crown 4-Ether is a functionalized crown ether derivative featuring a hydroxymethyl pendant group on the 12-crown-4 macrocyclic framework. This compound is valued for its selective ion-binding properties, particularly for lithium ions, making it a critical component in advanced separation and sensing technologies. It is essential for researchers and manufacturers in the fields of lithium extraction, battery electrolyte formulation, and the development of chemical sensors and phase-transfer catalysts.

Application

• Lithium Ionophore for Sensors: A key component in ion-selective electrodes (ISEs) and optical sensors for the selective detection and quantification of lithium ions in clinical and environmental samples.
• Lithium Extraction & Separation: Used as a selective complexing agent in solvent extraction processes for the recovery and purification of lithium from brines, ores, and recycled battery materials.
• Battery Electrolyte Additive: Investigated as an additive in lithium-ion and lithium-metal battery electrolytes to improve lithium-ion transport, stabilize the electrode-electrolyte interface, and enhance cycle life.
• Phase-Transfer Catalyst (PTC): Facilitates reactions between reagents in immiscible phases (e.g., aqueous and organic) by selectively complexing and transporting cations into the organic phase.
• Organic Synthesis & Molecular Recognition: Serves as a building block for synthesizing more complex host molecules and as a model compound in supramolecular chemistry studies for cation recognition.
• Analytical Chemistry Reagent: Employed in chromatographic separations and as a masking agent in analytical procedures to selectively bind and separate lithium from interfering ions.

Basic Information

Product Name	2-(Hydroxymethyl)-12-Crown 4-Ether
CAS No.	75507-26-5
Molecular Formula	C9H18O5
Molecular Weight	206.24 g/mol
Synonyms	12-Crown-4, 2-(hydroxymethyl)-; 2-(Hydroxymethyl)-1,4,7,10-tetraoxacyclododecane; Hydroxymethyl-12-crown-4; 2-(Hydroxymethyl)-12-crown-4; 12-Crown-4-2-methanol; Lithium ionophore VI; 1,4,7,10-Tetraoxacyclododecane-2-methanol
EINECS	Contact for details

Quality Control

Our 2-(Hydroxymethyl)-12-Crown 4-Ether is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and Karl Fischer titration for water content, to ensure it meets the high standards required for research and industrial applications. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere such as nitrogen or argon for long-term storage to prevent moisture absorption and potential degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.