Description

3,3,6,6-Tetramethylbicyclo[2.2.1]Heptane-2-One-5-Thione is a specialized, high-purity bicyclic thioketone compound of significant interest in advanced organic synthesis. This molecule matters as a versatile and structurally unique building block, offering a rigid, sterically hindered framework that is critical for developing novel materials and complex molecular architectures. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for applications in catalysis, ligand design, and the synthesis of high-value intermediates.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those requiring rigid, three-dimensional scaffolds.
• Catalyst & Ligand Synthesis: Used to develop novel organocatalysts and metal-chelating ligands for asymmetric synthesis and polymerization processes.
• Agrochemical Research: Acts as a building block for creating new crop protection agents with unique modes of action.
• Material Science: Employed in the research and development of advanced polymers, resins, and organic electronic materials due to its stable, hindered structure.
• Flavor & Fragrance Chemistry: Potential use in the synthesis of complex, musky or amber-type odorants where the thioketone group contributes to the scent profile.
• Academic & Industrial R&D: A valuable reagent for methodological studies in organic chemistry, including cycloaddition reactions and the exploration of new thiocarbonyl chemistry.

Basic Information

Product Name	3,3,6,6-Tetramethylbicyclo[2.2.1]Heptane-2-One-5-Thione
CAS No.	75503-13-8
Molecular Formula	C11H16OS
Molecular Weight	196.31 g/mol
Synonyms	2,5-Dithiabicyclo[2.2.1]heptane, 2,2,6,6-tetramethyl-3-oxo-; 5-Thioxo-2,2,6,6-tetramethylbicyclo[2.2.1]heptan-3-one; 2,2,6,6-Tetramethyl-3-oxo-2,5-dithiabicyclo[2.2.1]heptane; TMBD thione; Tetramethylbicycloheptanethione
EINECS	Contact for details

Quality Control

Our production of 3,3,6,6-Tetramethylbicyclo[2.2.1]Heptane-2-One-5-Thione adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is fully characterized and undergoes rigorous analytical testing, including HPLC, GC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from strong oxidizing agents and strong bases. For long-term storage, consider under an inert atmosphere to maximize stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.