Description

Tricyclo[3.2.1.02,4]Octane-1-Carboxylic Acid, (1Alpha,2Alpha,4Alpha,5Beta)- (9Ci) is a specialized, high-purity carboxylic acid derivative characterized by its unique, rigid tricyclic framework. This compound serves as a critical chiral building block and advanced intermediate in sophisticated organic synthesis, enabling the construction of complex molecular architectures. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in developing novel active ingredients and high-value specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new therapeutic agents, particularly in central nervous system (CNS) and antiviral drug candidates.
• Asymmetric Synthesis: Employed as a precursor or auxiliary in catalytic asymmetric reactions to induce stereoselectivity.
• Ligand and Catalyst Development: Used to synthesize novel, sterically demanding ligands for transition metal catalysis.
• Material Science Research: Serves as a monomer or functional additive in the development of polymers with specific thermal or mechanical properties.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry and for creating compound libraries for screening.

Basic Information

Product Name	Tricyclo[3.2.1.02,4]Octane-1-Carboxylic Acid, (1Alpha,2Alpha,4Alpha,5Beta)- (9Ci)
CAS No.	75421-02-2
Molecular Formula	C9H12O2
Molecular Weight	152.19 g/mol
Synonyms	(1α,2α,4α,5β)-Tricyclo[3.2.1.02,4]octane-1-carboxylic acid; endo-Tricyclo[3.2.1.02,4]octane-1-carboxylic acid; 1-Carboxytricyclo[3.2.1.02,4]octane; Bicyclo[2.2.2]oct-5-ene-2-carboxylic acid derivative (related synthon); 75421-02-2; TCO-acid derivative; Rigid bicyclic carboxylic acid
EINECS	Contact for details

Quality Control

Our production of this high-value intermediate adheres to strict quality management protocols. Every batch is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to ensure identity, purity, and stereochemical integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical parameters. Our quality systems are designed to support cGMP and ISO standards for traceability and consistency, making this product suitable for demanding R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its carboxylic acid nature, it should be stored separately from strong bases and oxidizing agents. Keep the container tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.