Description

6-Hydroxyhexyl p-Toluenesulfonate is a versatile organic intermediate featuring both a reactive tosylate leaving group and a terminal hydroxyl functionality. This dual reactivity makes it a valuable building block for the synthesis of more complex molecules, particularly in pharmaceutical and specialty chemical manufacturing. It is primarily sought after by research chemists and process development scientists in the fine chemical, pharmaceutical, and polymer industries for constructing molecular scaffolds and introducing functional groups.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for introducing hexyl-linked chains or creating prodrugs.
• Polymer Chemistry: Used as a monomer or cross-linking agent in the production of specialty polymers, coatings, and resins.
• Liquid Crystal Synthesis: Serves as a precursor in the manufacturing of certain liquid crystal compounds for display technologies.
• Surface Modification Agent: Employed to functionalize surfaces or materials by attaching organic chains via the tosylate group.
• Organic Synthesis Reagent: Utilized in nucleophilic substitution reactions to install protected or further derivatizable hydroxyhexyl groups.
• Bioconjugation Linker: Potential use in creating linkers for attaching molecules to biomolecules or solid supports in diagnostic and research applications.

Basic Information

Product Name	6-Hydroxyhexyl p-Toluenesulfonate
CAS No.	75351-33-6
Molecular Formula	C₁₃H₂₀O₄S
Molecular Weight	272.36 g/mol
Synonyms	6-Hydroxyhexyl Tosylate; 6-Hydroxyhexyl 4-Methylbenzenesulfonate; 1-Hexanol, 6-[(4-methylphenyl)sulfonyl]-; p-Toluenesulfonic Acid 6-Hydroxyhexyl Ester; Tosic Acid 6-Hydroxyhexyl Ester; 6-(Tosyloxy)hexan-1-ol; Hexane-1,6-diol monotosylate
EINECS	Contact for details

Quality Control

Our 6-Hydroxyhexyl p-Toluenesulfonate is produced under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong oxidizing agents, strong acids, and strong bases. The compound may be hygroscopic; handle and store under anhydrous conditions if specified for a particular grade.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0% (Typical 98-99%)
Assay	≥ 96.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.