Description

Polyquaternium-1 is a synthetic, polymeric quaternary ammonium compound widely recognized for its potent antimicrobial and preservative efficacy. This multifunctional polymer is valued for its ability to provide broad-spectrum protection against bacteria, fungi, and other microbes while maintaining excellent compatibility with a wide range of formulations. It is a critical ingredient for manufacturers in the ophthalmic, personal care, and pharmaceutical industries seeking a reliable and gentle preservative system.

Application

• Ophthalmic Solutions: Primary use as a preservative in artificial tears, contact lens rewetting drops, and multi-dose eye care products.
• Personal Care Products: Used as a preservative in shampoos, conditioners, skin creams, and liquid soaps to extend shelf life.
• Pharmaceutical Formulations: Employed as an antimicrobial agent in topical creams, ointments, and nasal sprays.
• Wound Care Products: Incorporated into antiseptic creams and hydrogel dressings for its disinfectant properties.
• Cosmetic Products: Functions as a conditioning agent and preservative in mascara, eyeliners, and other color cosmetics.
• Industrial Biocides: Potential application in water treatment and as a preservative in industrial fluids and coatings.

Basic Information

Product Name	Polyquaternium-1
CAS No.	75345-27-6
Molecular Formula	(C9H20N+·Cl-)n
Molecular Weight	Variable (Polymer)
Synonyms	Poly[(dimethyliminio)-1,3-propanediyl(dimethyliminio)-1,6-hexanediyl dichloride]; Onamer M; Polyquat 1; Polyquaternium 1; PQ-1; Quaternium-42; 1,6-Hexanediamine, N,N'-bis[3-(dimethylamino)propyl]-, polymer with 1,3-dichloropropane; Poly(oxy-1,2-ethanediyl), α-[2-[bis[3-(dimethylamino)propyl]amino]ethyl]-ω-hydroxy-, N,N'-dioxide, chlorides
EINECS	278-194-7

Quality Control

Our Polyquaternium-1 is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. It is produced in compliance with cGMP guidelines suitable for pharmaceutical and cosmetic applications. A comprehensive Certificate of Analysis (COA) is provided with each shipment, detailing key parameters such as assay, residual solvents, and microbial limits to meet your specific quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and excessive heat. The product is hygroscopic; ensure containers are sealed after use to prevent moisture absorption.

Specification

Item	Specification
Appearance	Clear to pale yellow viscous liquid
Identification (IR)	Conforms
Assay (Active Content)	40.0 - 50.0 % w/w
pH (10% solution)	5.0 - 7.0
Viscosity	Contact for details
Residual Solvents (GC)	Meets ICH limits
Heavy Metals	< 20 ppm
Microbial Limits	< 100 CFU/g (Total Aerobic Count) Absent (Pathogens)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.