Description

3-Bromo-1,1-dimethoxy-2-propanone is a versatile brominated ketone acetal intermediate with significant synthetic utility. This compound is valued for its reactivity as an electrophilic building block, enabling the introduction of functionalized acetone units into more complex molecular architectures. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for applications in organic synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of active pharmaceutical ingredients (APIs), particularly those containing β-keto or α-bromoketone functionalities.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and other crop protection agents where its reactive bromine and ketone groups are leveraged.
• Fine Chemical Manufacturing: Serves as a versatile precursor for specialty chemicals, dyes, and complex organic molecules in research and development.
• Cross-Coupling Reactions: Acts as an electrophilic partner in various metal-catalyzed cross-coupling reactions to form new carbon-carbon bonds.
• Heterocyclic Chemistry: Employed in the construction of heterocyclic compounds, which are core structures in many drugs and functional materials.
• Material Science Research: Investigated as a monomer or functionalizing agent in the development of novel polymers and advanced materials.

Basic Information

Product Name	3-Bromo-1,1-dimethoxy-2-propanone
CAS No.	75271-94-2
Molecular Formula	C5H9BrO3
Molecular Weight	197.03 g/mol
Synonyms	3-Bromo-1,1-dimethoxyacetone; 2-Propanone, 3-bromo-1,1-dimethoxy-; Bromoacetonedimethylacetal; 3-Bromoacetonedimethylacetal; 1,1-Dimethoxy-3-bromo-2-propanone; α-Bromoacetonedimethylacetal; Acetone, bromo-, dimethyl acetal; Bromodimethoxyacetone
EINECS	Contact for details

Quality Control

Our 3-Bromo-1,1-dimethoxy-2-propanone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopic methods (NMR, IR), to ensure high purity and consistent performance. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong bases and oxidizing agents. The container should be kept tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC/GC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.