Description

1-Methanesulfonyl-2-Methoxy-4-Nitrobenzene is a specialized nitroaromatic sulfone derivative that serves as a valuable synthetic intermediate in advanced organic chemistry. Its unique structure, featuring both electron-withdrawing nitro and methanesulfonyl groups, makes it a critical building block for constructing complex molecules with specific electronic and steric properties. This high-purity intermediate is essential for research and development in the pharmaceutical and agrochemical sectors, where it is used to create novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly in the development of kinase inhibitors and other targeted therapeutics.
• Agrochemical Synthesis: Used in the production of advanced herbicides and pesticides, where its nitroaromatic core contributes to biological activity.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Buchwald-Hartwig) and nucleophilic aromatic substitution to introduce functionalized benzene rings.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers and advanced organic electronic materials.
• Dye and Pigment Intermediate: Utilized in the synthesis of complex azo dyes and high-performance pigments due to its stable nitro-substituted structure.
• Chemical Research & Development: A versatile reagent for academic and industrial R&D labs exploring new synthetic methodologies and compound libraries.

Basic Information

Product Name	1-Methanesulfonyl-2-Methoxy-4-Nitrobenzene
CAS No.	75259-30-2
Molecular Formula	C8H9NO5S
Molecular Weight	231.22 g/mol
Synonyms	2-Methoxy-4-nitro-1-(methylsulfonyl)benzene; 4-Nitro-2-methoxy-1-(methylsulfonyl)benzene; 1-(Methylsulfonyl)-2-methoxy-4-nitrobenzene; Methanesulfonyl-2-methoxy-4-nitrobenzene; NSC 405124; 2-Methoxy-4-nitrobenzenesulfonylmethane; 4-Nitro-2-methoxybenzenesulfonylmethane
EINECS	Contact for details

Quality Control

Our 1-Methanesulfonyl-2-Methoxy-4-Nitrobenzene is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation by IR and NMR spectroscopy. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.