Description

1,3-Dioxolane-4-Carboxylicacid,5-(Hydroxymethyl)-,(4R-Trans)-(9Ci) is a high-purity chiral building block and protected form of glyceric acid, characterized by its specific stereochemistry. This compound is valued for its role as a versatile synthetic intermediate in the production of complex, stereochemically defined molecules. It is primarily required by research institutions and manufacturers in the pharmaceutical and fine chemical industries for applications in asymmetric synthesis and the development of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key chiral synthon in the asymmetric synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Fine Chemical Synthesis: Used in the preparation of specialty chemicals, ligands, and catalysts requiring specific stereochemistry.
• Biochemical Research: Serves as a protected precursor in the study and synthesis of glyceric acid derivatives and related metabolic compounds.
• Glycochemistry: Acts as a building block for the synthesis of carbohydrate analogs and complex sugar derivatives.
• Agrochemical Development: Employed in the research and production of chiral agrochemicals and plant growth regulators.

Basic Information

Product Name	1,3-Dioxolane-4-Carboxylicacid,5-(Hydroxymethyl)-,(4R-Trans)-(9Ci)
CAS No.	75201-59-1
Molecular Formula	C5H8O5
Molecular Weight	148.11 g/mol
Synonyms	(4R)-5-(Hydroxymethyl)-1,3-dioxolane-4-carboxylic acid; (R)-5-(Hydroxymethyl)-1,3-dioxolane-4-carboxylic acid; (R)-Glyceric acid 1,2-acetonide; (4R)-2,2-Dimethyl-1,3-dioxolane-4-carboxylic acid, 5-hydroxymethyl-; (R)-2,2-Dimethyl-1,3-dioxolane-4-acetic acid, α-hydroxy-; (R)-1,2-O-Isopropylidene glyceric acid; D-Glyceric acid 1,2-acetonide; (R)-Glyceric acid acetonide
EINECS	Contact for details

Quality Control

Our 1,3-Dioxolane-4-Carboxylicacid,5-(Hydroxymethyl)-,(4R-Trans)-(9Ci) is produced under strict quality management systems to ensure batch-to-batch consistency and high purity. The product undergoes rigorous analytical testing, including chiral purity verification, to meet the stringent requirements of pharmaceutical R&D and manufacturing. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.