Description

4-(tert-Butoxycarbonylamino)-1-Butanol is a versatile Boc-protected amino alcohol building block of significant importance in synthetic organic chemistry. Its primary value lies in providing a protected amine functionality, which is crucial for the controlled, stepwise synthesis of complex molecules, particularly peptides and other nitrogen-containing compounds. This intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity, reliable starting materials for advanced synthesis.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), especially in peptide and peptidomimetic drug discovery and development.
• Peptide Synthesis: Serves as a protected amino alcohol component in solid-phase and solution-phase peptide synthesis, enabling the incorporation of specific functional groups.
• Linker Chemistry: Used in the preparation of conjugates and bioconjugates, such as antibody-drug conjugates (ADCs), where a stable, cleavable linker is required.
• Agrochemical Synthesis: Intermediate in the production of certain herbicides, fungicides, and plant growth regulators that contain amino alcohol motifs.
• Polymer Modification: Employed to introduce functional amine groups into polymer backbones for creating specialty polymers with tailored properties.
• Research & Development: A valuable reagent in academic and industrial R&D labs for exploring new synthetic methodologies and creating novel chemical entities.

Basic Information

Product Name	4-(tert-Butoxycarbonylamino)-1-Butanol
CAS No.	75178-87-9
Molecular Formula	C9H19NO3
Molecular Weight	189.25 g/mol
Synonyms	N-Boc-4-amino-1-butanol; 4-[(tert-Butoxycarbonyl)amino]-1-butanol; 1-Butanol, 4-[[(1,1-dimethylethoxy)carbonyl]amino]-; N-(4-Hydroxybutyl)carbamic Acid tert-Butyl Ester; Boc-4-Aminobutanol; 4-(Boc-amino)butan-1-ol; tert-Butyl (4-hydroxybutyl)carbamate; N-Boc-4-aminobutanol
EINECS	Contact for details

Quality Control

Our 4-(tert-Butoxycarbonylamino)-1-Butanol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.