Description

3-Methoxybutyl Chloroformate is a versatile chloroformate ester used as a key reagent in organic synthesis, particularly for the introduction of protective groups and the synthesis of active pharmaceutical ingredients (APIs). Its value lies in its reactivity as an acylating agent, enabling efficient and selective chemical transformations under controlled conditions. This compound is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity intermediates for complex molecule construction.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of various active pharmaceutical ingredients (APIs) and drug candidates.
• Carbamate Protecting Group Reagent: Used to introduce the 3-methoxybutyloxycarbonyl (Moc) protecting group for amines in multi-step organic synthesis.
• Agrochemical Synthesis: Serves as an intermediate in the production of advanced herbicides, fungicides, and insecticides.
• Polymer Chemistry: Employed in the modification of polymers and as a monomer or cross-linking agent for specialty polymeric materials.
• Peptide Synthesis: Can be utilized in solution-phase peptide coupling strategies and for protecting amino acid derivatives.
• Chemical Research & Development: A valuable tool for academic and industrial R&D laboratories exploring new synthetic methodologies.

Basic Information

Product Name	3-Methoxybutyl Chloroformate
CAS No.	75032-87-0
Molecular Formula	C6H11ClO3
Molecular Weight	166.60 g/mol
Synonyms	Chloroformic Acid 3-Methoxybutyl Ester; 3-Methoxybutyl Carbonochloridate; 3-Methoxybutyl Chlorocarbonate; 1-Chloroformyloxy-3-methoxybutane; Butyl Chloroformate, 3-methoxy-; 3-Methoxybutanol Chloroformate; 75032-87-0; Moc-Cl (3-methoxybutyl variant)
EINECS	Contact for details

Quality Control

Every batch of 3-Methoxybutyl Chloroformate is manufactured and tested under strict quality management systems to ensure consistency and reliability for industrial applications. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity. Keep away from heat, sparks, open flames, and incompatible materials such as strong bases, alcohols, and amines.

Specification

Item	Specification
Appearance	Clear, colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Density (at 20°C)	~1.10 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.