Description

Lithium Difluoroacetate is a high-purity lithium salt of difluoroacetic acid, a valuable organofluorine building block. This compound is essential for introducing the difluoromethyl group into target molecules, a key modification in advanced material and pharmaceutical synthesis. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing novel fluorinated compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs) containing the difluoromethyl moiety, which can improve metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the research and production of modern pesticides and herbicides, where fluorination enhances activity and environmental persistence.
• Organic Synthesis Reagent: Serves as a versatile reagent in nucleophilic substitution and coupling reactions to incorporate -CF2H groups into complex organic frameworks.
• Electrolyte Additive Research: Investigated for use in advanced lithium-ion battery electrolytes to improve interfacial stability and cycle life.
• Material Science: Employed in the development of fluorinated polymers and specialty materials with unique surface properties and chemical resistance.
• Chemical Research: A fundamental building block in academic and industrial R&D for exploring new fluorination methodologies and creating novel chemical entities.

Basic Information

Product Name	Lithium Difluoroacetate
CAS No.	74956-94-8
Molecular Formula	C2HF2LiO2
Molecular Weight	103.97 g/mol
Synonyms	Difluoroacetic Acid Lithium Salt; Lithium 2,2-Difluoroacetate; 2,2-Difluoroacetic Acid Lithium Salt; LiDFA; Lithium α,α-Difluoroacetate; Lithium Difluoroethanoate; Difluoroacetate Lithium Salt
EINECS	Contact for details

Quality Control

Our Lithium Difluoroacetate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including purity assay and impurity profile via validated methods. A Certificate of Analysis (COA) detailing specifications and test results is available for every batch upon request, supporting your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Heavy Metals (as Pb)	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.