Description

N,4-Dimethyl-n-[(S)-α-Methylphenethyl]Benzenesulfonamide is a chiral sulfonamide derivative of significant interest in advanced organic synthesis. This compound matters as a key chiral intermediate or resolving agent for the production of enantiomerically pure pharmaceuticals and fine chemicals. Industries that need it include pharmaceutical R&D, agrochemical manufacturing, and specialty chemical synthesis, where precise stereochemistry is critical for product efficacy and regulatory approval.

Application

• Pharmaceutical Intermediate: Serves as a chiral building block or resolving agent in the synthesis of active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Synthesis Catalyst/ Ligand: Used in the development of chiral catalysts or auxiliaries for stereoselective chemical reactions.
• Agrochemical Research: Employed in the research and development of enantiomerically pure herbicides, fungicides, and plant growth regulators.
• Fine Chemical Production: Acts as a precursor for high-value specialty chemicals requiring specific stereochemical configurations.
• Academic & Industrial R&D: Utilized in research laboratories for method development in chiral separation and asymmetric synthesis studies.

Basic Information

Product Name	N,4-Dimethyl-n-[(S)-α-Methylphenethyl]Benzenesulfonamide
CAS No.	74810-23-4
Molecular Formula	C17H21NO2S
Molecular Weight	303.42 g/mol
Synonyms	Benzenesulfonamide, N,4-dimethyl-N-[(1S)-1-phenylethyl]-; (S)-N-(1-Phenylethyl)-4-methylbenzenesulfonamide; N,4-Dimethyl-N-[(S)-α-methylbenzyl]benzenesulfonamide; (S)-N,4-Dimethyl-N-(1-phenylethyl)benzenesulfonamide; p-Toluenesulfonamide, N-methyl-N-[(S)-1-phenylethyl]-; (S)-N-Methyl-N-(1-phenylethyl)-4-methylbenzenesulfonamide; Chiral Sulfonamide Derivative 74810-23-4
EINECS	Contact for details

Quality Control

Our N,4-Dimethyl-n-[(S)-α-Methylphenethyl]Benzenesulfonamide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity assay and identification of key impurities, to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) detailing purity, enantiomeric excess, and physical characteristics are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.