Description

Diphenethylzinc is an organozinc reagent characterized by its two phenethyl ligands, making it a valuable source of a nucleophilic phenethyl anion equivalent. This compound matters for its role as a key intermediate in advanced organic synthesis, particularly for carbon-carbon bond formation reactions like cross-couplings and nucleophilic additions. Industries involved in pharmaceutical development, agrochemical research, and materials science require high-purity organometallic reagents like Diphenethylzinc CAS NO 74685-32-8 to facilitate complex molecular construction.

Application

• Pharmaceutical Intermediate Synthesis: Employed as a key building block for introducing the phenethyl moiety into active pharmaceutical ingredients (APIs) and complex organic molecules.
• Agrochemical Research & Development: Used in the synthesis of novel pesticide and herbicide candidates that require specific aromatic alkyl groups.
• Cross-Coupling Reactions: Acts as a transmetalation agent in Negishi and related cross-coupling protocols to form biaryl and other C-C bonds.
• Nucleophilic Addition Reactions: Serves as a source of a stabilized carbanion for 1,2-additions to carbonyl compounds (aldehydes, ketones) and imines.
• Polymer & Materials Science: Utilized in the synthesis of specialized monomers or as an initiator/modifier in the production of advanced polymeric materials.
• Fine Chemical Manufacturing: Applied in the production of specialty chemicals, flavors, fragrances, and liquid crystals where precise structural control is essential.
• Academic & Industrial R&D: A critical reagent for methodological development in synthetic organic chemistry laboratories.

Basic Information

Item	Details
Product Name	Diphenethylzinc
CAS No.	74685-32-8
Molecular Formula	C16H18Zn
Molecular Weight	275.70 g/mol
Synonyms	Bis(2-phenylethyl)zinc; Zinc, bis(2-phenylethyl)-; Phenethylzinc; (2-Phenylethyl)zinc; Di(phenethyl)zinc; Zn(EtPh)2; Organozinc reagent (phenethyl); Zinc bis(phenethyl)
EINECS	Contact for details

Quality Control

Our Diphenethylzinc is produced and handled under stringent quality protocols, typically offered in research and development grades. Each batch undergoes rigorous analytical testing, including NMR and titration methods, to ensure consistency and purity. Certificates of Analysis (COA) detailing assay, identity, and impurity profiles are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Due to its highly volatile, hygroscopic (moisture-sensitive), and easily oxidized (store under inert atmosphere) nature, this material must be stored under an inert atmosphere (argon or nitrogen) in a cool, dry place. Recommended storage temperature is 2-8°C or as specified on the label. Keep away from heat, sparks, and open flames.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (NMR)	Conforms to structure
Assay (Titration)	≥ 0.5 M in specified solvent (e.g., THF, Toluene)
Purity (Zn basis)	Contact for details
Solvent	As specified (Typical: Tetrahydrofuran, Toluene)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.