Description

2,2,4,9,9-Pentamethyl-5-[(Trimethylsilyl)Oxy]-3,8-Dioxa-2,9-Disiladecane is a specialized organosilicon compound, CAS NO 74685-21-5, valued for its role as a versatile silylating agent and protecting group in advanced organic synthesis. Its molecular architecture, featuring multiple silyl ether linkages, provides exceptional reactivity and selectivity for modifying hydroxyl and other functional groups. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise molecular control to develop novel active ingredients and functional polymers.

Application

• Pharmaceutical Intermediate: Used as a key protecting group reagent in the multi-step synthesis of complex drug molecules, particularly for sensitive hydroxyl groups.
• Agrochemical Synthesis: Employed in the production of advanced pesticides and herbicides where selective silylation is required to control reactivity.
• Polymer & Material Science: Serves as a monomer or modifying agent in the development of silicone-based polymers, resins, and specialty coatings with tailored properties.
• Organic Synthesis Reagent: Acts as a versatile silylating agent in academic and industrial R&D labs for the protection of alcohols, phenols, and carboxylic acids.
• Surface Modification: Utilized to functionalize silica, glass, or other oxide surfaces, altering their hydrophobicity and reactivity for specific applications.
• Chiral Auxiliary Precursor: Can be used in the synthesis of chiral silane compounds for asymmetric synthesis applications.

Basic Information

Item	Details
Product Name	2,2,4,9,9-Pentamethyl-5-[(Trimethylsilyl)Oxy]-3,8-Dioxa-2,9-Disiladecane
CAS No.	74685-21-5
Molecular Formula	C15H38O3Si4
Molecular Weight	402.88 g/mol
Synonyms	1,3-Bis(trimethylsiloxy)-1,1,3,3-tetramethyldisiloxane; 1,3-Bis[(trimethylsilyl)oxy]-1,1,3,3-tetramethyldisiloxane; Bis(trimethylsiloxy)tetramethyldisiloxane; Tetramethyl-1,3-bis(trimethylsiloxy)disiloxane; 1,1,3,3-Tetramethyl-1,3-bis(trimethylsiloxy)disiloxane; HMDSO derivative; Disiloxane, 1,3-bis[(trimethylsilyl)oxy]-1,1,3,3-tetramethyl-
EINECS	Contact for details

Quality Control

Our 2,2,4,9,9-Pentamethyl-5-[(Trimethylsilyl)Oxy]-3,8-Dioxa-2,9-Disiladecane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC, NMR, and Karl Fischer titration, to ensure high purity and consistency suitable for demanding synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use to prevent evaporation and potential concentration changes. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (GC)	≥ 98.0%
Water Content (KF)	≤ 0.1%
Refractive Index (n20D)	1.3900 - 1.3950
Density (20°C)	0.85 - 0.90 g/mL

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.