Description

2,3-Dihydro-6-Hydroxy-1,1,3,3-Tetramethyl-1H-Indene-5-Carboxylic Acid is a specialized organic acid derivative of the indene family, characterized by its tetramethyl-substituted structure. This compound is valued for its role as a key synthetic intermediate and building block in advanced organic synthesis, where its unique sterically hindered phenolic acid structure enables precise molecular construction. It is primarily utilized by research institutions and industrial R&D departments in the pharmaceutical, agrochemical, and fine chemical sectors for developing novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel drug candidates and active pharmaceutical ingredients (APIs), particularly for compounds requiring sterically hindered phenolic motifs.
• Agrochemical Synthesis: Used in the research and development of advanced pesticides, herbicides, and plant growth regulators where its structural framework contributes to biological activity.
• Fine Chemical Building Block: Acts as a versatile synthon in organic chemistry for constructing complex molecules, including dyes, pigments, and specialty polymers.
• Material Science Research: Employed in the development of advanced organic materials, such as ligands for catalysis or components for organic electronic devices.
• Academic & Industrial R&D: A valuable reagent for methodological studies in synthetic organic chemistry, enabling new reaction pathways and functional group transformations.

Basic Information

Product Name	2,3-Dihydro-6-Hydroxy-1,1,3,3-Tetramethyl-1H-Indene-5-Carboxylic Acid
CAS No.	74475-27-7
Molecular Formula	C₁₄H₁₈O₃
Molecular Weight	234.29 g/mol
Synonyms	5-Carboxy-2,3-dihydro-6-hydroxy-1,1,3,3-tetramethyl-1H-indene; 6-Hydroxy-1,1,3,3-tetramethyl-2,3-dihydro-1H-indene-5-carboxylic acid; 1H-Indene-5-carboxylic acid, 2,3-dihydro-6-hydroxy-1,1,3,3-tetramethyl-; Tetramethylhydroindene carboxylic acid derivative; TMHICA (abbrev.); Sterically hindered phenolic acid intermediate.
EINECS	Contact for details

Quality Control

Our production of 2,3-Dihydro-6-Hydroxy-1,1,3,3-Tetramethyl-1H-Indene-5-Carboxylic Acid adheres to stringent quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR, to ensure it meets precise customer specifications and internal standards. Certificates of Analysis (COA) documenting all critical parameters are available upon request, providing full traceability and quality assurance for your R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible materials such as strong oxidizing agents. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.