Description

2-o-[3-Acetyl-1-(Trimethylsilyl)-1H-Indolyl]-3,4,5,6-Tetrakis-o-(Trimethylsilyl)-D-Glucose 1-(o-Methyloxime) is a sophisticated, fully protected carbohydrate derivative designed for advanced synthetic chemistry. This compound is a critical high-value intermediate, offering precise control over glycosylation and functional group manipulation in complex molecule assembly. It is primarily utilized by research and development teams in the pharmaceutical and biotechnology sectors for the synthesis of novel glycoconjugates, nucleoside analogs, and other bioactive molecules.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of complex glycoconjugates and nucleoside-based active pharmaceutical ingredients (APIs).
• Glycobiology Research: Used in the study of carbohydrate-protein interactions and the development of carbohydrate-based vaccines and diagnostics.
• Medicinal Chemistry: Enables the introduction of protected sugar moieties into lead compounds for structure-activity relationship (SAR) studies.
• Process Chemistry: Serves as a high-purity intermediate in the scalable production of specialty fine chemicals and advanced materials.
• Chemical Biology: Employed in the synthesis of labeled probes and tools for investigating biological pathways involving carbohydrates.

Basic Information

Item	Details
Product Name	2-o-[3-Acetyl-1-(Trimethylsilyl)-1H-Indolyl]-3,4,5,6-Tetrakis-o-(Trimethylsilyl)-D-Glucose 1-(o-Methyloxime)
CAS No.	74421-39-9
Molecular Formula	C₃₄H₆₃NO₈Si₅
Molecular Weight	786.36 g/mol
Synonyms	1,2,3,4,6-Penta-O-trimethylsilyl-2-O-[3-acetyl-1-(trimethylsilyl)-1H-indol-2-yl]-D-glucose O-methyloxime; Fully Silylated Glucose-Indole Derivative; 2-O-(3-Acetyl-1-trimethylsilylindol-2-yl)-1,3,4,5,6-penta-O-trimethylsilyl-D-glucose O-methyloxime; Protected D-Glucose Indole Conjugate; CAS 74421-39-9
EINECS	Contact for details

Quality Control

Every batch of this advanced intermediate is produced and tested under strict quality management protocols to ensure consistency and purity for sensitive synthetic applications. We provide comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles as determined by HPLC, NMR, and mass spectrometry. Our quality systems support development under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment, and consideration should be given to handling under an inert atmosphere for long-term storage or after opening.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.