Description

(R)-3-(Benzoylthio)-2-Methylpropionic Acid is a high-purity chiral building block and pharmaceutical intermediate of significant commercial interest. Its value lies in its stereochemically defined structure, which is crucial for the synthesis of enantiomerically pure active pharmaceutical ingredients (APIs). This compound is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for developing novel therapeutics and specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and production of enantiomerically pure drugs, particularly in cardiovascular and metabolic disease research.
• Asymmetric Synthesis: Used as a building block in stereoselective chemical reactions to construct complex molecular architectures.
• Protease Inhibitor Research: Serves as a precursor or core structure in the development of enzyme inhibitors targeting various proteases.
• Agrochemical Development: Employed in the synthesis of advanced, chiral active ingredients for crop protection products.
• Ligand and Catalyst Preparation: Utilized for the preparation of specialized ligands and organocatalysts used in asymmetric catalysis.
• Academic & Process R&D: A valuable reagent for method development and scaling novel synthetic routes in academic and industrial R&D laboratories.

Basic Information

Product Name	(R)-3-(Benzoylthio)-2-Methylpropionic Acid
CAS No.	74407-70-8
Molecular Formula	C11H12O3S
Molecular Weight	224.27 g/mol
Synonyms	(R)-3-(Benzoylthio)-2-methylpropanoic acid; (R)-2-Methyl-3-(benzoylthio)propionic Acid; (R)-α-Methyl-β-(benzoylthio)propionic Acid; (R)-MBA; (R)-3-Benzoylthio-2-methylpropionic Acid; D-3-(Benzoylthio)-2-methylpropionic Acid; (R)-3-Benzoylthio-2-methylpropanoic Acid; (2R)-3-(Benzoylthio)-2-methylpropanoic Acid
EINECS	Contact for details

Quality Control

Our (R)-3-(Benzoylthio)-2-Methylpropionic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and production. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere (e.g., nitrogen or argon) to preserve stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%, Total impurities ≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.