Description

(3Z)-7-(Trifluoromethyl)-1H-Indole-2,3-Dione 3-Oxime is a specialized organic compound belonging to the isatin oxime class, characterized by its trifluoromethyl substituent which imparts unique electronic and steric properties. This compound serves as a versatile and high-value synthetic intermediate for constructing complex molecular architectures in advanced research and development. It is primarily needed by pharmaceutical, agrochemical, and material science R&D teams for applications in medicinal chemistry, crop protection, and functional material synthesis.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Research: Used in developing advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Organic Synthesis & Catalysis: Serves as a precursor for ligands in transition metal catalysis and as a scaffold for constructing heterocyclic compounds.
• Material Science: Investigated for the development of organic semiconductors, dyes, and photoactive materials due to its electron-withdrawing characteristics.
• Academic & Industrial R&D: Employed in chemical libraries for high-throughput screening and structure-activity relationship (SAR) studies.

Basic Information

Item	Details
Product Name	(3Z)-7-(Trifluoromethyl)-1H-Indole-2,3-Dione 3-Oxime
CAS No.	74396-78-4
Molecular Formula	C9H5F3N2O2
Molecular Weight	230.15 g/mol
Synonyms	7-(Trifluoromethyl)isatin 3-oxime; (3Z)-7-(Trifluoromethyl)-1H-indole-2,3-dione 3-oxime; 7-Trifluoromethylisatin-3-oxime; 1H-Indole-2,3-dione, 7-(trifluoromethyl)-, 3-oxime, (3Z)-; 74396-78-4; 7-Trifluoromethyl-1H-indole-2,3-dione 3-oxime; (Z)-7-(Trifluoromethyl)isatin oxime
EINECS	Contact for details

Quality Control

Our (3Z)-7-(Trifluoromethyl)-1H-Indole-2,3-Dione 3-Oxime is produced under a strict quality management system. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay, impurity profile, and physical characteristics. Our quality commitment supports cGMP and ISO 9001 standards for reliable supply to critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents and bases. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.