Description

2-Deoxy-3-O,4-O,5-O,6-o-Tetrakis(Trimethylsilyl)-2-[(Trimethylsilyl)Amino]-D-Glucose o-Methyl Oxime is a highly functionalized, fully silylated carbohydrate derivative, serving as a critical protected intermediate in advanced organic synthesis. Its value lies in providing a stable, reactive scaffold for the controlled construction of complex glycoconjugates and modified nucleosides. This compound is essential for researchers and manufacturers in pharmaceutical development, particularly for creating novel antiviral and anticancer agents, as well as for specialized carbohydrate chemistry in agrochemical and material science applications.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of modified nucleoside analogs used in antiviral and anticancer drug discovery.
• Glycoconjugate Synthesis: Protected precursor for the controlled assembly of complex oligosaccharides, glycopeptides, and glycolipids.
• Carbohydrate Chemistry Research: Essential reagent for studying glycosylation reactions, anomerization, and the development of new protecting group strategies.
• Agrochemical Development: Intermediate in the synthesis of novel, bioactive carbohydrate-based compounds for crop protection.
• Material Science: Potential monomer or modifier for creating specialized polymers with unique surface or biocompatibility properties.
• Diagnostic Reagents: Used in the development of labeled probes and sensors for biological detection systems.

Basic Information

Product Name	2-Deoxy-3-O,4-O,5-O,6-o-Tetrakis(Trimethylsilyl)-2-[(Trimethylsilyl)Amino]-D-Glucose o-Methyl Oxime
CAS No.	74367-65-0
Molecular Formula	C24H61NO5Si6
Molecular Weight	620.31 g/mol
Synonyms	2-Deoxy-2-(trimethylsilylamino)-3,4,5,6-tetra-O-trimethylsilyl-D-glucose O-methyloxime; D-Glucose, 2-deoxy-2-[(trimethylsilyl)amino]-, O-methyloxime, 3,4,5,6-tetra-O-trimethylsilyl-; Fully Silylated 2-Amino-2-deoxy-D-glucose Methyl Oxime; 2-Amino-2-deoxy-D-glucose oxime, per-O-trimethylsilyl, N-trimethylsilyl, O-methyl; TMS-protected D-Glucosamine Oxime Derivative; Hexakis(trimethylsilyl) Glucosamine Methyl Oxime
EINECS	Contact for details

Quality Control

Our 2-Deoxy-3-O,4-O,5-O,6-o-Tetrakis(Trimethylsilyl)-2-[(Trimethylsilyl)Amino]-D-Glucose o-Methyl Oxime is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including NMR (¹H, ¹³C), HPLC, and GC-MS, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. We support cGMP compliance for pharmaceutical applications and can tailor purity grades to meet specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled temperature of 2°C to 8°C (refrigerated). Due to its hygroscopic and highly volatile nature, the container must be kept sealed under an inert atmosphere (argon or nitrogen) when not in use to prevent moisture absorption and decomposition. Keep away from heat and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.