Description

15β-Hydroxy-3-[(Trimethylsilyl)Oxy]Estra-1,3,5(10)-Trien-17-One o-Methyl Oxime is a high-purity, advanced steroid derivative used as a critical synthetic intermediate. This compound is valued for its role in the production of complex pharmaceutical actives, particularly in the field of endocrinology and hormone research. It is primarily sought by research institutions, pharmaceutical development laboratories, and fine chemical manufacturers requiring precise and reliable building blocks for complex organic synthesis.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of steroidal drugs and active pharmaceutical ingredients (APIs).
• Research & Development: Used in academic and industrial laboratories for the study of steroid chemistry and metabolic pathways.
• Process Chemistry: Employed in scale-up and optimization of synthetic routes for complex organic molecules.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Biochemical Research: Utilized in studies involving hormone receptors and enzyme inhibition assays.

Basic Information

Product Name	15β-Hydroxy-3-[(Trimethylsilyl)Oxy]Estra-1,3,5(10)-Trien-17-One o-Methyl Oxime
CAS No.	74299-35-7
Molecular Formula	C23H39NO3Si
Molecular Weight	405.65 g/mol
Synonyms	15β-Hydroxy-3-[(trimethylsilyl)oxy]estra-1,3,5(10)-trien-17-one O-methyloxime; 15β-Hydroxy-3-trimethylsilyloxyestra-1,3,5(10)-trien-17-one O-methyloxime; 15β-Hydroxy-3-(trimethylsiloxy)estra-1,3,5(10)-trien-17-one O-methyloxime; 15β-Hydroxy-3-(trimethylsilyloxy)estra-1,3,5(10)-trien-17-one O-methyloxime; 15β-Hydroxy-3-(trimethylsilyloxy)estra-1,3,5(10)-trien-17-one methyloxime; 15β-Hydroxy-3-(trimethylsiloxy)-estra-1,3,5(10)-trien-17-one O-methyloxime; 15β-Hydroxy-3-(trimethylsilyloxy)estra-1,3,5(10)-trien-17-one O-methyl oxime; 15β-Hydroxy-3-[(trimethylsilyl)oxy]estra-1,3,5(10)-trien-17-one O-methyl oxime
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards. Each batch is analyzed using advanced techniques including HPLC, GC, and NMR to verify identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are available upon request. We adhere to a quality management system suitable for supplying materials for research and development purposes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and stored in a dark environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.