Description

3,6β,7α,17β-Tetrakis[(Trimethylsilyl)Oxy]Estra-1,3,5(10)-Triene is a high-purity, multi-silylated derivative of the estrane steroid nucleus, serving as a critical advanced intermediate in complex organic synthesis. Its value lies in providing a protected, reactive scaffold for the targeted development of novel steroid-based compounds and pharmaceutical agents. This product is essential for research chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries who require precise molecular building blocks for drug discovery and development programs.

Application

• Pharmaceutical Intermediate: Key protected intermediate in the multi-step synthesis of novel steroidal drugs and active pharmaceutical ingredients (APIs).
• Steroid Chemistry Research: Used as a versatile starting material or building block for exploring new chemical entities within the estrane series in academic and industrial R&D laboratories.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of complex steroid molecules, leveraging the stability of the trimethylsilyl (TMS) protecting groups.
• Reference Standard: Serves as a high-purity analytical standard for method development and quality control in the analysis of related steroid compounds and their synthetic pathways.

Basic Information

Product Name	3,6β,7α,17β-Tetrakis[(Trimethylsilyl)Oxy]Estra-1,3,5(10)-Triene
CAS No.	74298-84-3
Molecular Formula	C30H54O4Si4
Molecular Weight	591.10 g/mol
Synonyms	3,6β,7α,17β-Tetrakis(trimethylsilyloxy)estra-1,3,5(10)-triene; Estra-1,3,5(10)-triene-3,6β,7α,17β-tetrol, tetrakis(trimethylsilyl) ether; 3,6β,7α,17β-Tetrakis-O-(trimethylsilyl)estra-1,3,5(10)-triene; TMS-Estrane Tetrol Derivative; 3,6,7,17-Tetrakis(trimethylsiloxy)estra-1,3,5(10)-triene
EINECS	Contact for details

Quality Control

Our 3,6β,7α,17β-Tetrakis[(Trimethylsilyl)Oxy]Estra-1,3,5(10)-Triene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR), to ensure it meets the high standards required for synthetic applications. Certificates of Analysis (COA) with detailed batch-specific results are available upon request to support your quality and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). This compound is moisture-sensitive; keep the container tightly sealed under an inert atmosphere such as nitrogen or argon to prevent degradation. Store away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.