Description

1-(Mesitylene-2-Sulfonyl)-3-Nitro-1,2,4-Triazole is a specialized heterocyclic sulfonamide compound, identified by CAS NO 74257-00-4. This high-value intermediate is critical for advanced organic synthesis, offering a unique mesitylenesulfonyl protecting group and a reactive nitro-triazole scaffold. It is primarily sought after by research chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in nucleoside and active pharmaceutical ingredient (API) synthesis.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel nucleoside analogs and antiviral/anticancer drug candidates.
• Agrochemical Research: Used in developing new active ingredients for crop protection products.
• Chemical Biology & Proteomics: Serves as a reagent for bioconjugation and activity-based protein profiling due to its reactive sulfonyl group.
• Polymer Chemistry: Potential monomer or cross-linking agent for creating specialty polymers with specific thermal or chemical properties.
• Material Science Research: Investigated for use in advanced materials, such as energetic materials or liquid crystals.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO laboratories.

Basic Information

Product Name	1-(Mesitylene-2-Sulfonyl)-3-Nitro-1,2,4-Triazole
CAS No.	74257-00-4
Molecular Formula	C12H12N4O4S
Molecular Weight	308.31 g/mol
Synonyms	1-(2,4,6-Trimethylbenzenesulfonyl)-3-nitro-1,2,4-triazole; 3-Nitro-1-(2,4,6-trimethylphenylsulfonyl)-1,2,4-triazole; 1-Mesitylsulfonyl-3-nitro-1,2,4-triazole; MSNT; 1,2,4-Triazole, 1-[(2,4,6-trimethylphenyl)sulfonyl]-3-nitro-; 1-(2,4,6-Trimethylphenylsulfonyl)-3-nitro-1,2,4-triazole
EINECS	Contact for details

Quality Control

Our 1-(Mesitylene-2-Sulfonyl)-3-Nitro-1,2,4-Triazole is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity for research and development applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry standards for fine chemical production, and specifications can be aligned with customer-specific requirements for advanced synthetic work.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maximize stability. Keep away from strong oxidizing agents and strong bases.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.