Description

(±)-n-Ethoxycarbonylnornicotine is a specialized synthetic intermediate of significant interest in advanced organic synthesis and pharmaceutical research. This compound serves as a crucial building block for the development of novel nicotinic receptor ligands and other bioactive molecules. It is primarily utilized by research institutions and pharmaceutical development companies engaged in medicinal chemistry and neuropharmacology.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel nicotinic acetylcholine receptor (nAChR) modulators and other central nervous system (CNS) active compounds.
• Medicinal Chemistry Research: Used as a versatile scaffold for structure-activity relationship (SAR) studies to develop new therapeutic agents.
• Chemical Reference Standard: Serves as a high-purity analytical standard for quality control and method development in research laboratories.
• Organic Synthesis Building Block: Employed in multi-step synthetic routes to create complex alkaloid derivatives and other nitrogen-containing heterocycles.
• Neuroscience Research: Utilized in the study of nicotine analogs and their biochemical interactions at receptor sites.

Basic Information

Product Name	(±)-n-Ethoxycarbonylnornicotine
CAS No.	74245-32-2
Molecular Formula	C13H18N2O2
Molecular Weight	234.30 g/mol
Synonyms	Ethyl Nornicotinate; Ethyl 5-((S)-1-Methyl-2-pyrrolidinyl)-3-pyridinecarboxylate (racemic); 3-[(2S)-1-Methylpyrrolidin-2-yl]pyridine-5-carboxylic acid ethyl ester (±)-form; rac-Ethyl Nornicotinate; N-Ethoxycarbonylnornicotine; 5-Carbethoxy-3-(1-methyl-2-pyrrolidinyl)pyridine; 3-Pyridinecarboxylic acid, 5-[(2S)-1-methyl-2-pyrrolidinyl]-, ethyl ester, (±)-
EINECS	Contact for details

Quality Control

Our (±)-n-Ethoxycarbonylnornicotine is produced under strict quality management protocols to ensure batch-to-batch consistency and high purity suitable for research applications. Each lot is characterized by advanced analytical techniques including HPLC, GC-MS, and NMR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profile is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.