Description

3-Bromo-5-Methylphenol is a halogenated phenolic compound that serves as a versatile and valuable synthetic intermediate in advanced organic chemistry. Its molecular structure, featuring both a bromine substituent and a phenolic hydroxyl group, makes it a critical building block for constructing more complex molecules with tailored properties. This compound is primarily sought after by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications in drug discovery, ligand synthesis, and polymer modification.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring halogenated aromatic motifs.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in metal-catalyzed coupling reactions and coordination chemistry.
• Polymer Chemistry: Incorporated as a monomer or modifier to impart flame retardancy or alter the thermal and solubility properties of engineering plastics and resins.
• Organic Synthesis Building Block: Employed in cross-coupling reactions (e.g., Suzuki, Heck) and nucleophilic aromatic substitution to create complex biaryl and heterocyclic structures.
• Material Science Research: Used in the development of advanced organic electronic materials and liquid crystals.

Basic Information

Product Name	3-Bromo-5-Methylphenol
CAS No.	74204-00-5
Molecular Formula	C7H7BrO
Molecular Weight	187.04 g/mol
Synonyms	5-Methyl-3-bromophenol; 3-Bromo-5-cresol; 3-Bromo-5-hydroxytoluene; 5-Bromo-3-methylphenol; 3-Bromo-m-cresol; 1-Bromo-3-hydroxy-5-methylbenzene; m-Cresol, 3-bromo-; Phenol, 3-bromo-5-methyl-
EINECS	Contact for details

Quality Control

Our 3-Bromo-5-Methylphenol is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. We provide comprehensive Certificates of Analysis (COA) for each lot, detailing key parameters such as assay, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, and we support our clients' regulatory needs for pharmaceutical and agrochemical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Due to its sensitivity to oxidation, it is recommended to store under an inert atmosphere (e.g., nitrogen or argon) for long-term preservation. Keep away from strong oxidizing agents, strong bases, and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	65 - 70 °C
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.