Description

(3R)-4,5-Dihydro-3α-Methyl-5β-[(E)-3-Methyl-1,3-Butadienyl]-2(3H)-Furanone is a high-purity, optically active lactone derivative with a specific stereochemical configuration. This compound serves as a critical chiral building block and intermediate in the synthesis of complex organic molecules, where its defined stereochemistry is essential for directing subsequent reactions. It is primarily required by pharmaceutical research and development teams, fine chemical manufacturers, and academic laboratories engaged in the synthesis of active pharmaceutical ingredients (APIs), fragrances, and advanced materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of novel therapeutic agents and active pharmaceutical ingredients (APIs).
• Asymmetric Synthesis: Utilized as a building block in stereoselective reactions to construct complex molecular architectures with high enantiomeric purity.
• Fragrance and Flavor Chemistry: Serves as a precursor for the development of specific lactone-based odorants and flavor compounds.
• Agrochemical Research: Employed in the research and development of new chiral active ingredients for crop protection.
• Material Science: Investigated as a monomer or intermediate for the synthesis of specialized polymers and advanced organic materials.
• Academic and Process Chemistry: Used in methodological studies and scale-up process development for complex organic transformations.

Basic Information

Product Name	(3R)-4,5-Dihydro-3α-Methyl-5β-[(E)-3-Methyl-1,3-Butadienyl]-2(3H)-Furanone
CAS No.	74133-35-0
Molecular Formula	C11H16O2
Molecular Weight	180.24 g/mol
Synonyms	(3R)-3-Methyl-5-[(1E)-3-methylbuta-1,3-dien-1-yl]dihydrofuran-2(3H)-one; (R)-3-Methyl-5-[(E)-3-methyl-1,3-butadienyl]dihydro-2(3H)-furanone; (3R)-3-Methyl-5-[(E)-3-methylbuta-1,3-dien-1-yl]dihydrofuran-2(3H)-one; Optically Active Lactone Derivative CAS 74133-35-0; Chiral Dihydrofuranone Intermediate
EINECS	Contact for details

Quality Control

Our (3R)-4,5-Dihydro-3α-Methyl-5β-[(E)-3-Methyl-1,3-Butadienyl]-2(3H)-Furanone is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity assessment by HPLC, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing identity, purity, and chiral excess are provided with each shipment to guarantee traceability and consistency for your critical processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.