Description

3-(Trifluoromethyl)Cyclohex-2-En-1-One is a versatile fluorinated building block and key synthetic intermediate prized for its unique chemical reactivity. Its structure, featuring a reactive enone moiety adjacent to a trifluoromethyl group, makes it a critical precursor for introducing fluorine-containing motifs into complex molecules. This compound is essential for research chemists and process developers in the pharmaceutical and agrochemical industries seeking to enhance the metabolic stability, lipophilicity, and bioavailability of target compounds.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides, where the trifluoromethyl group can improve biological activity and environmental persistence.
• Material Science Precursor: Acts as a monomer or cross-linking agent in the production of specialty polymers and coatings with enhanced chemical resistance and unique surface properties.
• Organic Synthesis Building Block: Employed in Michael additions, Diels-Alder reactions, and other cyclization processes to construct complex, fluorinated carbo- and heterocyclic frameworks.
• Ligand and Catalyst Development: Utilized for creating novel chiral ligands and organocatalysts used in asymmetric synthesis.
• Fluorine Chemistry Research: A fundamental reagent for academic and industrial research exploring new methodologies for C-F bond formation and functionalization.

Basic Information

Product Name	3-(Trifluoromethyl)Cyclohex-2-En-1-One
CAS No.	74031-45-1
Molecular Formula	C7H7F3O
Molecular Weight	164.13 g/mol
Synonyms	3-(Trifluoromethyl)-2-cyclohexen-1-one; 3-(Trifluoromethyl)cyclohex-2-enone; 2-Cyclohexen-1-one, 3-(trifluoromethyl)-; 3-Trifluoromethyl-2-cyclohexen-1-one; 3-Trifluoromethylcyclohex-2-enone; 3-(Trifluoromethyl)-δ²-cyclohexenone; 3-TFMCH
EINECS	Contact for details

Quality Control

Our 3-(Trifluoromethyl)Cyclohex-2-En-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chromatography (HPLC/GC) and spectroscopy (NMR, IR, MS), to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our commitment to supply chain integrity and documentation transparency supports your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The container should be kept tightly closed in a dry and well-ventilated place. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.