Description

Avermectin is a highly potent macrocyclic lactone compound widely recognized for its exceptional anthelmintic and insecticidal properties. Its core value lies in its ability to act as a highly effective agonist at glutamate-gated chloride channels, leading to paralysis and death in target parasites and insects. This makes it a critical active ingredient for manufacturers in the agricultural, veterinary pharmaceutical, and animal health sectors. Its broad-spectrum efficacy against nematodes and arthropods underpins its global importance in crop protection and livestock management.

Application

• Agricultural Insecticide/Acaricide: As a key component in formulations for controlling mites, leaf miners, and other pests on a wide range of crops including fruits, vegetables, and ornamentals.
• Veterinary Antiparasitic Formulations: Used in the production of injectables, pour-ons, and oral drenches for the treatment and control of internal and external parasites (e.g., roundworms, lice, mites) in livestock and companion animals.
• Animal Health Premixes: Incorporated into feed-grade products for the prophylactic control of parasitic infections in poultry, swine, and cattle.
• Public Health Pest Control: An active ingredient in products targeting disease-vector insects, such as mosquitoes, in certain public health programs.
• Research & Development: Serves as a reference standard and starting material for biochemical research, pharmacological studies, and the development of novel semi-synthetic derivatives like Ivermectin.
• Specialty Crop Protection: Used in integrated pest management (IPM) programs for high-value crops where its specific mode of action and favorable environmental profile are advantageous.

Basic Information

Product Name	Avermectin
CAS No.	73989-17-0
Molecular Formula	C48H72O14 (B1a component)
Molecular Weight	873.09 g/mol (B1a)
Synonyms	Avermectin B1; Abamectin; Avermectin B1a; MK-936; Avermectin A; C 076; Affirm; Agri-Mek; Avid; Vertimec; Zephyr; Avermectin complex; 5-O-Demethylavermectin A1a; (10E,14E,16E)-(1R,4S,5'S,6R,6'R,8R,12S,13S,20R,21R,24S)-6'-[(S)-sec-butyl]-21,24-dihydroxy-5',11,13,22-tetramethyl-2-oxo-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6-spiro-2'-(5',6'-dihydro-2'H-pyran)-12-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-α-L-arabino-hexopyranosyl)-3-O-methyl-α-L-arabino-hexopyranoside
EINECS	277-634-4

Quality Control

Our Avermectin is produced and tested under a strict quality management system to ensure batch-to-batch consistency and compliance with relevant industry standards. Quality parameters are verified through advanced analytical techniques including HPLC for precise assay and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and related substances is provided with each shipment to guarantee product integrity for your formulations.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 92.0% (Avermectin B1a + B1b)
Avermectin B1a (HPLC)	≥ 80.0%
Related Substances (HPLC)	Total impurities ≤ 8.0%
Loss on Drying	≤ 2.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.