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1,1-Diethyl-3-(m-Hydroxyphenyl)Urea tert-Butylcarbamate CAS NO 73953-76-1


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CAS No.:73953-76-1

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

1,1-Diethyl-3-(m-Hydroxyphenyl)Urea tert-Butylcarbamate is a specialized organic compound featuring a urea core substituted with diethyl and tert-butylcarbamate protecting groups, along with a meta-hydroxyphenyl moiety. This unique structure makes it a valuable protected intermediate and building block in advanced organic synthesis, particularly for pharmaceuticals and agrochemicals. It is essential for research and development chemists in the fine chemical and life sciences industries who require high-purity, structurally complex intermediates for constructing novel active molecules.

Application

  • Pharmaceutical Intermediate: Serves as a key protected precursor in the synthesis of complex drug candidates, especially those targeting central nervous system (CNS) disorders.
  • Agrochemical Research: Used as a building block for developing new active ingredients in crop protection products, such as herbicides and fungicides.
  • Peptide Mimetics & PROTACs: The urea and carbamate functionalities make it suitable for constructing peptide bond isosteres and linkers in Proteolysis-Targeting Chimeras (PROTACs).
  • Chemical Biology Probes: Employed in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.
  • Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects requiring specific, protected functional groups.
  • Material Science Research: Potential monomer or cross-linking agent in the development of specialty polymers with specific thermal or mechanical properties.

Basic Information

Product Name 1,1-Diethyl-3-(m-Hydroxyphenyl)Urea tert-Butylcarbamate
CAS No. 73953-76-1
Molecular Formula C16H24N2O4
Molecular Weight 308.37 g/mol
Synonyms 1,1-Diethyl-3-(3-hydroxyphenyl)urea tert-butylcarbamate; tert-Butyl N-[1,1-diethyl-3-(3-hydroxyphenyl)ureido]carbamate; 1,1-Diethyl-3-(3-hydroxyphenyl)urea N-Boc derivative; Boc-Protected 1,1-Diethyl-3-(m-hydroxyphenyl)urea; N-(tert-Butoxycarbonyl)-N'-[1,1-diethyl-3-(3-hydroxyphenyl)urea]; Urea, N-(1,1-diethyl-3-(3-hydroxyphenyl)-, N'-carboxylic acid tert-butyl ester; 73953-76-1
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Quality Control

Our 1,1-Diethyl-3-(m-Hydroxyphenyl)Urea tert-Butylcarbamate is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. We provide a detailed Certificate of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to cGMP principles and REACH compliance guarantees a reliable supply of high-purity material for your most demanding applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from heat, sparks, and open flame.

Specification

Item Specification
Appearance White to off-white crystalline powder
Identification (IR) Conforms to structure
Identification (HPLC) Retention time matches reference standard
Assay (HPLC) ≥ 98.0%
Related Substances (HPLC) Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying ≤ 0.5%
Residue on Ignition ≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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