Description

(R)-n-Benzylglutamic Acid CAS NO 73914-82-6 is a high-purity, single-enantiomer amino acid derivative of significant importance in advanced pharmaceutical synthesis and chiral research. This compound serves as a critical chiral building block and resolving agent for the development of active pharmaceutical ingredients (APIs) and fine chemicals. It is primarily utilized by research institutions, pharmaceutical R&D departments, and fine chemical manufacturers engaged in asymmetric synthesis and the production of specialized peptides or drug candidates.

Application

• Chiral Intermediate in Pharmaceutical Synthesis: A key starting material or intermediate for synthesizing enantiomerically pure drugs, particularly in neurological and metabolic disorder research.
• Peptide Chemistry & Modification: Used to introduce the (R)-benzylglutamic acid moiety into peptide chains to alter biological activity, stability, or receptor binding properties.
• Asymmetric Catalyst & Ligand Preparation: Serves as a precursor for chiral ligands and organocatalysts used in stereoselective chemical transformations.
• Biochemical Research & Proteomics: Employed in studies of enzyme mechanisms, receptor-ligand interactions, and as a standard in analytical method development.
• Resolution of Racemic Mixtures: Acts as a chiral resolving agent to separate enantiomers of other acids or amines.
• Fine Chemical & Specialty Product Manufacturing: Incorporated into high-value agrochemicals, flavors, fragrances, and advanced materials requiring specific stereochemistry.

Basic Information

Product Name	(R)-n-Benzylglutamic Acid
CAS No.	73914-82-6
Molecular Formula	C12H15NO4
Molecular Weight	237.25 g/mol
Synonyms	(R)-2-(Benzylamino)pentanedioic acid; D-(-)-N-Benzylglutamic Acid; (R)-N-Benzyl-L-glutamic Acid; N-Benzyl-D-glutamic Acid; (2R)-2-(Benzylamino)pentanedioic acid; (R)-Nα-Benzylglutamic Acid; Nα-Benzyl-D-glutamic Acid; (R)-BGA
EINECS	Contact for details

Quality Control

Our (R)-n-Benzylglutamic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and fine chemical synthesis. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment. We support compliance with cGMP, ICH Q7, and relevant pharmacopeial guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥98.0%
Enantiomeric Excess (Chiral HPLC)	≥99.0%
Loss on Drying	≤1.0%
Residue on Ignition (Sulfated Ash)	≤0.1%
Heavy Metals (as Pb)	≤20 ppm
Related Substances (HPLC)	Individual impurity ≤0.5%; Total impurities ≤1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.