Description

2H-Pyran-3-Carboxylicacid,4-Aminotetrahydro-6-Methoxy-2-Methyl-,Methylester,(2Alpha,3Beta,4Beta,6Alpha)- is a high-purity, stereochemically defined heterocyclic compound that serves as a critical chiral building block in advanced organic synthesis. Its value lies in its complex, functionalized pyran core, which provides a versatile scaffold for constructing pharmacologically active molecules. This intermediate is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents and fine chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in classes like antivirals, neurological agents, or complex natural product derivatives.
• Asymmetric Synthesis: Utilized in stereoselective reactions to introduce multiple chiral centers into target molecules, leveraging its defined (2α,3β,4β,6α) configuration.
• Medicinal Chemistry Research: Employed in lead optimization and structure-activity relationship (SAR) studies to explore new chemical spaces for drug discovery programs.
• Fine Chemical Production: Serves as a precursor in the multi-step synthesis of specialty chemicals, agrochemicals, and other high-value compounds requiring a functionalized tetrahydropyran moiety.
• Academic & Process Chemistry: Used in university and industrial labs for methodological development, catalysis studies, and scaling up synthetic routes.

Basic Information

Product Name	2H-Pyran-3-Carboxylicacid,4-Aminotetrahydro-6-Methoxy-2-Methyl-,Methylester,(2Alpha,3Beta,4Beta,6Alpha)-
CAS No.	73844-74-3
Molecular Formula	C9H15NO4
Molecular Weight	201.22 g/mol
Synonyms	Methyl (2α,3β,4β,6α)-4-amino-6-methoxy-2-methyltetrahydro-2H-pyran-3-carboxylate; (2α,3β,4β,6α)-4-Amino-6-methoxy-2-methyltetrahydro-2H-pyran-3-carboxylic acid methyl ester; 4-Amino-6-methoxy-2-methyltetrahydro-2H-pyran-3-carboxylic acid methyl ester (stereoisomer); Tetrahydro-2H-pyran-3-carboxylic acid, 4-amino-6-methoxy-2-methyl-, methyl ester, (2α,3β,4β,6α)-; CAS 73844-74-3
EINECS	Contact for details

Quality Control

Our production of this advanced intermediate adheres to strict quality management protocols, ensuring batch-to-batch consistency and high chemical purity suitable for research and development. Each lot is characterized using advanced analytical techniques including HPLC, GC, NMR, and chiral analysis to confirm identity, purity, and stereochemical integrity. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.