Description

2-Chloro-2-Methylbutyric Acid is a versatile chlorinated carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce both a tertiary alkyl halide and a carboxylic acid functional group, enabling the construction of complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key starting material or intermediate in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring a branched chloroalkane moiety.
• Agrochemical Synthesis: Used in the production of herbicides, fungicides, and plant growth regulators where its structure contributes to biological activity.
• Organic Synthesis Reagent: Employed as an alkylating agent or as a precursor for esters, amides, and other derivatives in fine chemical and academic research laboratories.
• Polymer Chemistry: Acts as a monomer or chain-transfer agent in the production of specialized polymers and coatings with tailored properties.
• Ligand and Catalyst Preparation: Useful for synthesizing chiral auxiliaries, ligands for asymmetric catalysis, and other organometallic compounds.

Basic Information

Product Name	2-Chloro-2-Methylbutyric Acid
CAS No.	73758-54-0
Molecular Formula	C5H9ClO2
Molecular Weight	136.58 g/mol
Synonyms	2-Chloro-2-methylbutanoic acid; α-Chloroisovaleric acid; 2-Methyl-2-chlorobutyric acid; 2-Chloro-2-methylbutyric acid; Butanoic acid, 2-chloro-2-methyl-; NSC 163045
EINECS	Contact for details

Quality Control

Our 2-Chloro-2-Methylbutyric Acid is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including assay by titration, identification by IR spectroscopy, and impurity profiling by GC or HPLC, to ensure it meets precise customer specifications and industry standards. Certificates of Analysis (COA) documenting purity, identity, and safety parameters are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases and oxidizing agents. Recommended storage temperature is 2-25°C. Due to its nature as a strong acid/organic solvent, handle with appropriate personal protective equipment and ensure containers are kept tightly sealed to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (Titration)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (GC/HPLC)	≤ 2.0% total

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.