Description

2,2,2-Trichloroethyl p-Nitrobenzenesulfonate is a specialized organic sulfonate ester, a key building block in advanced synthetic chemistry. This compound is valued for its role as an activated ester and protecting group reagent, enabling precise molecular transformations. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of complex molecules.

Application

• Pharmaceutical Intermediate: A crucial reagent in the multi-step synthesis of active pharmaceutical ingredients (APIs), particularly for introducing sulfonate ester functionalities.
• Protecting Group Chemistry: Used to protect hydroxyl groups during complex organic syntheses, with the trichloroethyl group being cleavable under specific conditions.
• Agrochemical Synthesis: Serves as a building block in the development of novel herbicides, fungicides, and other crop protection agents.
• Peptide Chemistry: Employed in the synthesis and modification of peptides and related biomolecules.
• Material Science Research: Used in the development of specialty polymers and functional materials requiring sulfonate linkages.
• Academic & Industrial R&D: A valuable tool for methodological development and exploring new chemical reactions in laboratory settings.

Basic Information

Product Name	2,2,2-Trichloroethyl p-Nitrobenzenesulfonate
CAS No.	73688-65-0
Molecular Formula	C8H6Cl3NO5S
Molecular Weight	334.56 g/mol
Synonyms	p-Nitrobenzenesulfonic Acid 2,2,2-Trichloroethyl Ester; 2,2,2-Trichloroethyl 4-Nitrobenzenesulfonate; 4-Nitrobenzenesulfonic Acid Trichloroethyl Ester; Trichloroethyl p-Nosylate; Troc-ONs; Troc-ONs Reagent; 2,2,2-Trichloroethyl 4-Nitrobenzene-1-sulfonate; NSC 401071
EINECS	Contact for details

Quality Control

Our 2,2,2-Trichloroethyl p-Nitrobenzenesulfonate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as assay and impurity profiles. Our quality commitment ensures the material meets the stringent requirements for research and process chemistry applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider inert atmosphere conditions to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Heavy Metals	< 20 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.