Description

8-(p-Fluorophenyl)-6-Trifluoromethyl-1,2,4-Triazolo(4,3-B)Pyridazine is a high-value, fluorinated heterocyclic compound that serves as a critical building block in advanced chemical synthesis. Its unique molecular architecture, featuring both a fluorophenyl and a trifluoromethyl group fused to a triazolopyridazine core, makes it an essential intermediate for developing novel active ingredients. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for creating new drug candidates and crop protection agents with enhanced properties.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in areas targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and insecticides, where the fluorine atoms can improve metabolic stability, bioavailability, and binding affinity.
• Material Science Precursor: Serves as a specialized building block for developing advanced organic electronic materials, such as those used in OLEDs or semiconductors, due to its electron-deficient aromatic system.
• Chemical Biology Probe: Utilized in medicinal chemistry to create molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring complex fluorinated heterocycles.

Basic Information

Product Name	8-(p-Fluorophenyl)-6-Trifluoromethyl-1,2,4-Triazolo(4,3-B)Pyridazine
CAS No.	73673-80-0
Molecular Formula	C₁₂H₆F₄N₄
Molecular Weight	282.20 g/mol
Synonyms	8-(4-Fluorophenyl)-6-(trifluoromethyl)-[1,2,4]triazolo[4,3-b]pyridazine; 6-Trifluoromethyl-8-(p-fluorophenyl)-1,2,4-triazolo[4,3-b]pyridazine; 8-(4-Fluorophenyl)-6-(trifluoromethyl)-1,2,4-triazolo[4,3-b]pyridazine; 1,2,4-Triazolo[4,3-b]pyridazine, 8-(4-fluorophenyl)-6-(trifluoromethyl)-; 73673-80-0; FC-1133 (Potential Research Code)
EINECS	Contact for details

Quality Control

Every batch of 8-(p-Fluorophenyl)-6-Trifluoromethyl-1,2,4-Triazolo(4,3-B)Pyridazine is manufactured and tested under a strict quality management system. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are available upon request. We support cGMP (current Good Manufacturing Practice) standards for pharmaceutical-grade material upon inquiry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single unknown impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.