Description

Methyl 4-Aza-5Alpha-Androsta-3-One-17Beta-Carboxylate is a high-purity steroid derivative and a key pharmaceutical intermediate. This compound is valued for its role in the synthesis of more complex molecules, particularly in the research and development of therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic research institutions focused on medicinal chemistry and steroid-based drug discovery.

Application

• Pharmaceutical Intermediate: A critical building block in the multi-step synthesis of active pharmaceutical ingredients (APIs) targeting hormonal pathways.
• Medicinal Chemistry Research: Used in the discovery and development of novel steroid-based therapeutics, including potential anti-inflammatory and anti-cancer agents.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Research: Employed in studies investigating enzyme inhibition, receptor binding, and other steroid-related biochemical mechanisms.
• Process Development: Used for scaling up and optimizing synthetic routes in pilot plants and commercial manufacturing settings.

Basic Information

Product Name	Methyl 4-Aza-5Alpha-Androsta-3-One-17Beta-Carboxylate
CAS No.	73671-92-8
Molecular Formula	C₂₀H₃₁NO₃
Molecular Weight	333.47 g/mol
Synonyms	Methyl 4-aza-5α-androst-3-one-17β-carboxylate; 17β-Carbomethoxy-4-aza-5α-androstan-3-one; 4-Aza-5α-androstane-3-one-17β-carboxylic acid methyl ester; Finasteride intermediate; Finasteride related compound; 5α-Androst-3-one-17β-carboxylic acid, 4-aza-, methyl ester; Finasteride methyl ester analog
EINECS	Contact for details

Quality Control

Our Methyl 4-Aza-5Alpha-Androsta-3-One-17Beta-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and NMR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.