Description

5-(2-Pyridylmethylene)-2-Thiobarbituric Acid is a specialized thiobarbituric acid derivative characterized by its pyridylmethylene functional group, which imparts unique chelating and chromogenic properties. This compound is valued in research and industrial chemistry for its role as a versatile analytical reagent and a key synthetic intermediate. It is primarily utilized by professionals in pharmaceutical R&D, analytical laboratories, and fine chemical synthesis.

Application

• Analytical Chemistry Reagent: Used as a sensitive chromogenic agent for the spectrophotometric detection and quantification of metal ions, aldehydes, and other analytes.
• Pharmaceutical Intermediate: Serves as a crucial building block in the synthesis of novel heterocyclic compounds with potential biological activity.
• Biochemical Research: Employed in studies involving lipid peroxidation and as a probe for reactive carbonyl species due to its thiobarbituric acid reactivity.
• Material Science: Investigated for the development of organic ligands and coordination polymers for catalytic or sensing applications.
• Dye and Pigment Synthesis: Acts as a precursor for the preparation of functional dyes and colorants.
• Quality Control (QC) Testing: Applied in standardized methods for the analysis of specific impurities or degradation products in chemical and pharmaceutical products.

Basic Information

Product Name	5-(2-Pyridylmethylene)-2-Thiobarbituric Acid
CAS No.	73664-50-3
Molecular Formula	C11H8N2O2S
Molecular Weight	232.26 g/mol
Synonyms	5-[(Pyridin-2-yl)methylidene]-2-sulfanylidene-1,3-diazinane-4,6-dione; 5-(2-Pyridinylmethylene)-2-thioxodihydro-4,6(1H,5H)-pyrimidinedione; 2-Thiobarbituric acid, 5-(2-pyridylmethylene)-; PTBA; PMTBA; 5-(2-Pyridylmethylidene)thiobarbituric Acid; 5-(2-Pyridylmethylene)barbituric-2-thione
EINECS	Contact for details

Quality Control

Our 5-(2-Pyridylmethylene)-2-Thiobarbituric Acid is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial use. Certificates of Analysis (COA) documenting all critical parameters are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. Due to its light-sensitive nature, prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.