Description

Dehydrobruceine A is a bioactive quassinoid compound, a key intermediate and reference standard in pharmaceutical research and development. Its significance lies in its potent biological activity, making it a valuable tool for studying anti-cancer, anti-malarial, and anti-inflammatory mechanisms. This high-purity compound is essential for researchers and manufacturers in the pharmaceutical, biotechnology, and academic sectors who require reliable, well-characterized materials for drug discovery and quality control applications.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the identification, assay, and purity testing of bruceine-related APIs and herbal extracts.
• Drug Discovery & Development: Serves as a lead compound and pharmacological probe in oncology and parasitology research due to its cytotoxic and antiparasitic properties.
• Natural Product Isolation & Analysis: Acts as a critical marker compound for the quality control and standardization of medicinal plant extracts, particularly from the *Brucea* genus.
• Biochemical Research: Employed in in vitro and in vivo studies to investigate cellular pathways, apoptosis induction, and enzyme inhibition.
• Analytical Method Development: Utilized to develop and validate analytical methods such as HPLC, LC-MS, and TLC for complex natural product matrices.

Basic Information

Product Name	Dehydrobruceine A
CAS No.	73435-47-9
Molecular Formula	C20H24O9
Molecular Weight	408.40 g/mol
Synonyms	Dehydrobruceine A; 13,18-Dehydrobruceine A; NSC 330836; (1S,2R,6S,7R,11S,12R,13S,14R,15S,17S)-2,6,12,14,15-Pentahydroxy-4,4,8,13-tetramethyl-17-[(2S)-2-methyloxiran-2-yl]-3,16-dioxapentacyclo[11.7.0.0¹,¹⁵.0²,¹¹.0⁶,¹⁰]icosa-8,19-dien-9-one
EINECS	Contact for details

Quality Control

Our Dehydrobruceine A is produced and tested under a strict quality management system to ensure batch-to-batch consistency and high purity for research applications. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant industry guidelines for reference standards to support your regulatory and research requirements.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry environment. For long-term storage, consider storing desiccated at 2-8°C.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference
Identification (IR)	Conforms to structure
Purity (HPLC)	≥98.0%
Loss on Drying	≤1.0%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.