Description

4-(Hydroxymethyl)Phenylacetic Acid is a versatile aromatic carboxylic acid derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional structure, featuring both a carboxylic acid and a benzylic alcohol group, makes it a valuable intermediate for constructing complex molecules with high precision. This compound is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where it is used to develop active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key starting material or building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for anti-inflammatory and cardiovascular drugs.
• Peptide Synthesis: Used in the preparation of modified amino acids and as a linker or protecting group reagent in solid-phase peptide synthesis (SPPS).
• Agrochemical Synthesis: Intermediate in the production of herbicides, fungicides, and plant growth regulators.
• Liquid Crystal & Polymer Chemistry: Serves as a monomer or precursor for synthesizing specialty polymers and liquid crystal materials.
• Bioconjugation & Probe Development: Utilized for attaching labels, dyes, or other molecules to biomolecules in diagnostic and research applications.
• Fine Chemical & Catalyst Ligand Synthesis: Building block for creating complex ligands used in asymmetric catalysis and other fine chemical processes.

Basic Information

Product Name	4-(Hydroxymethyl)Phenylacetic Acid
CAS No.	73401-74-8
Molecular Formula	C9H10O3
Molecular Weight	166.17 g/mol
Synonyms	2-[4-(Hydroxymethyl)phenyl]acetic Acid; (4-Hydroxymethylphenyl)acetic Acid; 4-Carboxymethylbenzyl Alcohol; p-(Hydroxymethyl)phenylacetic Acid; 4-(Hydroxymethyl)benzeneacetic Acid; HMPAA; 4-HMPA; Contact for details on additional trade names.
EINECS	Contact for details

Quality Control

Our 4-(Hydroxymethyl)Phenylacetic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment. We can support compliance requirements for cGMP, ISO, and other relevant quality standards upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to prevent degradation. For long-term storage, consider using an inert atmosphere to minimize oxidation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Melting Point	110 - 115 °C
Heavy Metals	≤ 20 ppm
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.