Description

Cyclobutanone, 2-Chloro-3-Hydroxy-2,4,4-Trimethyl- is a specialized, high-purity organic building block with a unique sterically hindered structure. This compound matters as a critical chiral intermediate for synthesizing complex molecules in advanced pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists working on novel active ingredients, particularly in the fields of asymmetric synthesis and medicinal chemistry.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), especially in sterically demanding synthetic routes.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides where its specific stereochemistry imparts desired biological activity.
• Asymmetric Catalysis Research: Serves as a valuable substrate or ligand precursor in the development of new catalytic systems for stereoselective transformations.
• Fine Chemical Production: Employed in the manufacture of complex fragrance and flavor compounds requiring precise molecular architecture.
• Academic & Industrial R&D: A versatile building block for methodological studies in organic synthesis and material science.

Basic Information

Product Name	Cyclobutanone, 2-Chloro-3-Hydroxy-2,4,4-Trimethyl-
CAS No.	73199-38-9
Molecular Formula	C8H13ClO2
Molecular Weight	176.64 g/mol
Synonyms	2-Chloro-3-hydroxy-2,4,4-trimethylcyclobutanone; 2,4,4-Trimethyl-2-chloro-3-hydroxycyclobutanone; 3-Hydroxy-2-chloro-2,4,4-trimethylcyclobutanone; (2-Chloro-3-hydroxy-2,4,4-trimethylcyclobutyl) ketone; Cyclobutanone, 2-chloro-3-hydroxy-2,4,4-trimethyl-; 73199-38-9; 2-Chloro-2,4,4-trimethyl-3-hydroxycyclobutanone
EINECS	Contact for details

Quality Control

Our Cyclobutanone, 2-Chloro-3-Hydroxy-2,4,4-Trimethyl- is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chromatography and spectroscopic methods, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) with detailed specifications are provided to guarantee batch-to-batch consistency and support your regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. The compound is moisture-sensitive; keep container tightly sealed under an inert atmosphere if specified.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.