Description

(S)-(-)-3-(Benzoylthio)-2-Methylpropanoic Acid is a high-purity chiral building block and synthetic intermediate of significant importance in advanced organic synthesis. Its value lies in its defined stereochemistry and functional groups, which enable the precise construction of complex molecular architectures. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel active pharmaceutical ingredients (APIs), agrochemicals, and other fine chemicals where stereochemical control is critical.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new therapeutic agents, particularly for creating molecules with specific biological activity.
• Agrochemical Synthesis: Used in the production of advanced, stereoselective pesticides and herbicides where the (S)-enantiomer imparts desired biological properties.
• Asymmetric Catalysis Research: Serves as a precursor or ligand in the development of new chiral catalysts and auxiliaries for stereoselective transformations.
• Peptidomimetics & Bioactive Molecule Design: The thioester and carboxylic acid functionalities make it valuable for constructing peptide analogs and other bioactive scaffolds.
• Material Science Research: Potential monomer or building block for synthesizing specialized polymers with unique optical or chemical properties.
• Academic & Process Chemistry: A valuable tool for method development and studying sulfur-containing chiral compound reactivity in academic and industrial R&D labs.

Basic Information

Product Name	(S)-(-)-3-(Benzoylthio)-2-Methylpropanoic Acid
CAS No.	72679-02-8
Molecular Formula	C11H12O3S
Molecular Weight	224.27 g/mol
Synonyms	(S)-3-(Benzoylthio)-2-methylpropanoic acid; (S)-(-)-3-Benzoylthio-2-methylpropionic Acid; (S)-2-Methyl-3-(benzoylthio)propanoic acid; (S)-3-Benzoylthio-2-methylpropanoic acid; (S)-α-Methyl-β-(benzoylthio)propionic Acid; (S)-3-(Benzoylthio)-2-methylpropionic Acid; (S)-3-Benzoylthio-2-methylpropanoate; L-3-(Benzoylthio)-2-methylpropanoic acid
EINECS	Contact for details

Quality Control

Our production of (S)-(-)-3-(Benzoylthio)-2-Methylpropanoic Acid adheres to stringent quality management protocols to ensure batch-to-batch consistency and high chemical purity. Each lot is characterized and tested using advanced analytical techniques, including chiral HPLC, to confirm identity, enantiomeric excess (ee), and purity. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support cGMP-compliant manufacturing for pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The compound may be moisture-sensitive; keep the container tightly sealed under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.