Description

8-Methoxy-5-[(Methylprop-2-Ynylamino)Methyl]-3-Phenyl-2-Benzopyrone Hydrochloride is a high-purity synthetic organic compound belonging to the benzopyrone (coumarin) derivative class. This compound is of significant interest in advanced pharmaceutical research and development, particularly as a key intermediate or active pharmaceutical ingredient (API) precursor. It is primarily utilized by R&D laboratories, fine chemical manufacturers, and pharmaceutical companies engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel drug candidates, particularly those targeting neurological or cardiovascular pathways.
• Biochemical Research: Used as a reference standard or probe in pharmacological studies to investigate enzyme interactions and receptor binding mechanisms.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex molecules with potential biological activity.
• Academic R&D: Utilized in university and institutional laboratories for medicinal chemistry projects and the development of new synthetic methodologies.
• Preclinical Development: Acts as a starting material for producing batches of compounds required for early-stage toxicity and efficacy testing.

Basic Information

Product Name	8-Methoxy-5-[(Methylprop-2-Ynylamino)Methyl]-3-Phenyl-2-Benzopyrone Hydrochloride
CAS No.	72543-54-5
Molecular Formula	C22H22ClNO3
Molecular Weight	383.87 g/mol
Synonyms	5-[(Methyl-2-propynylamino)methyl]-8-methoxy-3-phenyl-1-benzopyran-2-one hydrochloride; 8-Methoxy-5-[(N-methyl-N-2-propynyl)aminomethyl]-3-phenylcoumarin hydrochloride; 3-Phenyl-8-methoxy-5-[(methylprop-2-yn-1-ylamino)methyl]-2H-chromen-2-one hydrochloride; Coumarin derivative 72543-54-5; 2H-1-Benzopyran-2-one, 5-[(methyl-2-propynylamino)methyl]-8-methoxy-3-phenyl-, hydrochloride; 3-Phenyl-8-methoxy-5-[(methylprop-2-ynylamino)methyl]coumarin hydrochloride
EINECS	Contact for details

Quality Control

Our 8-Methoxy-5-[(Methylprop-2-Ynylamino)Methyl]-3-Phenyl-2-Benzopyrone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and heavy metals to ensure it meets high-purity standards suitable for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.