Description

2-Methyl-2-Piperidine Carboxylic Acid is a versatile chiral piperidine derivative that serves as a critical building block in advanced organic synthesis. Its value lies in its ability to introduce a constrained, nitrogen-containing ring system, which is essential for modulating the biological activity and physicochemical properties of target molecules. This high-purity intermediate is primarily needed by pharmaceutical R&D and fine chemical manufacturers for applications in drug discovery, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. We ensure a reliable supply of this compound to support your most demanding synthesis projects.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the synthesis of novel drug candidates, particularly in central nervous system (CNS) and metabolic disorder research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the piperidine scaffold contributes to biological efficacy.
• Ligand and Catalyst Preparation: Serves as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the multistep synthesis of complex, high-value specialty chemicals and flavors & fragrances.
• Academic and R&D: A valuable reagent for methodological development in organic chemistry and medicinal chemistry research laboratories.
• Peptidomimetics: Incorporated into peptide analogs to enhance metabolic stability and bioavailability.

Basic Information

Product Name	2-Methyl-2-Piperidine Carboxylic Acid
CAS No.	72518-41-3
Molecular Formula	C7H13NO2
Molecular Weight	143.18 g/mol
Synonyms	2-Methylpipecolic Acid; 2-Methyl-2-piperidinecarboxylic Acid; (RS)-2-Methylpipecolic Acid; DL-2-Methylpipecolic Acid; 2-Methyl-2-carboxypiperidine; 2-Piperidinecarboxylic acid, 2-methyl-; 2-Methylpiperidine-2-carboxylic Acid
EINECS	Contact for details

Quality Control

Our 2-Methyl-2-Piperidine Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our quality commitment ensures batch-to-batch consistency and traceability for your regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.