Description

3-Hydroxydihydro-2H-Pyran-4(3H)-One is a versatile heterocyclic building block and chiral intermediate of significant interest in fine chemical synthesis. Its unique structure, featuring both hydroxyl and ketone functional groups on a dihydropyran ring, makes it a valuable precursor for pharmaceuticals, agrochemicals, and advanced materials. This compound is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: Key chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in developing antiviral, anticancer, and central nervous system (CNS) drugs.
• Agrochemical Synthesis: Used as a building block for creating novel herbicides, fungicides, and plant growth regulators with enhanced efficacy.
• Flavor & Fragrance Industry: Serves as a precursor for lactones and other compounds that contribute to creamy, fruity, or coconut-like notes in flavors and fragrances.
• Material Science Research: Employed in the development of novel polymers, ligands for catalysis, and organic frameworks due to its functional handle for further chemical modification.
• Asymmetric Catalysis: Utilized as a substrate or ligand precursor in stereoselective synthesis to induce chirality in target molecules.
• Academic & R&D Laboratories: A valuable reagent for methodological studies in organic chemistry, including cyclization and oxidation reactions.

Basic Information

Product Name	3-Hydroxydihydro-2H-Pyran-4(3H)-One
CAS No.	72250-01-2
Molecular Formula	C5H8O3
Molecular Weight	116.12 g/mol
Synonyms	3-Hydroxy-3,4-dihydro-2H-pyran-4-one; 4H-Pyran-4-one, 3-hydroxy-3,4-dihydro-; 3-Hydroxytetrahydro-4H-pyran-4-one; 3-Hydroxy-4H-pyran-4-one, 3,4-dihydro-; Tetrahydro-4H-pyran-4-one, 3-hydroxy-; 3-Hydroxydihydropyran-4-one
EINECS	Contact for details

Quality Control

Our 3-Hydroxydihydro-2H-Pyran-4(3H)-One is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment, ensuring full traceability and compliance with your internal quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (if applicable)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.