Description

(3R,6Aα,10Bα)-5α-Acetyloxy-3α-Vinyldodecahydro-6β-Hydroxy-3,4Aβ,7,7,10Aβ-Pentamethyl-1H-Naphtho[2,1-B]Pyran-1-One CAS NO 72243-75-5 is a high-purity, complex diterpenoid derivative with a specific stereochemical configuration. This compound is valued as a critical advanced pharmaceutical intermediate for the synthesis of novel therapeutic agents, particularly in steroid and terpenoid-based drug discovery. It is essential for research and development laboratories, pharmaceutical manufacturers, and fine chemical suppliers requiring precisely defined chiral building blocks for complex organic synthesis.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of novel steroid-mimetic drugs and bioactive terpenoids.
• Medicinal Chemistry Research: Used in R&D for structure-activity relationship (SAR) studies and the development of new chemical entities targeting various receptors.
• Organic Synthesis Building Block: Serves as a complex, polyfunctional starting material for total synthesis projects in academic and industrial settings.
• Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Biochemical Probe Development: Utilized in the creation of probes to study enzymatic pathways and biological mechanisms involving terpenoid metabolism.

Basic Information

Product Name	(3R,6Aα,10Bα)-5α-Acetyloxy-3α-Vinyldodecahydro-6β-Hydroxy-3,4Aβ,7,7,10Aβ-Pentamethyl-1H-Naphtho[2,1-B]Pyran-1-One
CAS No.	72243-75-5
Molecular Formula	C24H36O5
Molecular Weight	404.54 g/mol
Synonyms	5α-Acetoxy-3α-vinyldodecahydro-6β-hydroxy-3,4aβ,7,7,10aβ-pentamethyl-1H-naphtho[2,1-b]pyran-1-one; Labdane diterpenoid derivative; 3α-Vinyl-5α-acetoxy-6β-hydroxylabd-8-en-15-oic acid δ-lactone; (3R,4aS,6aS,10aS,10bR)-5-Acetyloxy-3-ethenyldodecahydro-6-hydroxy-3,4a,7,7,10a-pentamethyl-1H-naphtho[2,1-b]pyran-1-one; CAS 72243-75-5; Advanced labdane intermediate; Polycyclic diterpene lactone.
EINECS	Contact for details

Quality Control

Our (3R,6Aα,10Bα)-5α-Acetyloxy-3α-Vinyldodecahydro-6β-Hydroxy-3,4Aβ,7,7,10Aβ-Pentamethyl-1H-Naphtho[2,1-B]Pyran-1-One is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing including HPLC, NMR, and MS to ensure identity, purity, and stereochemical integrity. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support cGMP standards for pharmaceutical intermediate applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under inert atmosphere when appropriate to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.