Description

4-Chloro-3-Fluorobenzylamine is a versatile halogenated benzylamine derivative that serves as a critical building block in advanced organic synthesis. Its bifunctional nature, featuring both a reactive amine group and a halogenated aromatic ring, makes it an indispensable intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for the development of active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for molecules targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the chloro-fluoro substitution pattern enhances biological activity and stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Building block for synthesizing monomers and functional polymers with specific electronic or surface properties.
• Chemical Research: A valuable reagent in academic and industrial R&D for exploring novel heterocyclic compounds and conducting structure-activity relationship (SAR) studies.
• Dye and Pigment Intermediate: Employed in the synthesis of specialized colorants and functional dyes.

Basic Information

Product Name	4-Chloro-3-Fluorobenzylamine
CAS No.	72235-58-6
Molecular Formula	C7H7ClFN
Molecular Weight	159.59 g/mol
Synonyms	(4-Chloro-3-fluorophenyl)methanamine; 1-(Aminomethyl)-4-chloro-3-fluorobenzene; 4-Chloro-3-fluoro-benzenemethanamine; 3-Fluoro-4-chlorobenzylamine; Benzenemethanamine, 4-chloro-3-fluoro-; 4-Chloro-3-fluorobenzyl amine; FCBZA; 4-Chloro-3-fluoro-α-toluidine
EINECS	Contact for details

Quality Control

Our 4-Chloro-3-Fluorobenzylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment to guarantee compliance with your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach room temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.