Description

4-Chloro-2-Fluorobenzyl Amine is a versatile halogenated benzylamine building block of significant importance in advanced organic synthesis. Its bifunctional nature, featuring both a reactive amine group and a chloro-fluoro substituted aromatic ring, makes it a critical intermediate for constructing complex molecular architectures. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used to develop active ingredients and novel chemical entities.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of receptor modulators and enzyme inhibitors.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and pesticides, leveraging its halogenated aromatic structure.
• Ligand and Catalyst Development: Serves as a precursor for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of monomers for specialty polymers and advanced functional materials.
• Chemical Biology Probes: Utilized to create labeled compounds and molecular probes for biochemical and diagnostic research.
• Custom Synthesis and R&D: A fundamental starting material for contract research organizations (CROs) and fine chemical companies engaged in custom synthesis projects.

Basic Information

Product Name	4-Chloro-2-Fluorobenzyl Amine
CAS No.	72235-57-5
Molecular Formula	C7H7ClFN
Molecular Weight	159.59 g/mol
Synonyms	(4-Chloro-2-fluorophenyl)methanamine; 1-(4-Chloro-2-fluorophenyl)methanamine; 4-Chloro-2-fluorobenzylamine; 2-Fluoro-4-chlorobenzylamine; Benzenemethanamine, 4-chloro-2-fluoro-; 4-Chloro-2-fluoro-α-toluidine; α-Amino-4-chloro-2-fluorotoluene; (4-Chloro-2-fluorobenzyl)amine
EINECS	Contact for details

Quality Control

Our 4-Chloro-2-Fluorobenzyl Amine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or crystalline mass
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Individual impurity ≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.