Description

3-Chloro-2-Fluorobenzylamine is a versatile halogenated benzylamine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in its bifunctional nature, combining a reactive primary amine group with a halogen-substituted aromatic ring, enabling the construction of complex molecular architectures. This high-purity intermediate is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and anti-infective drug candidates.
• Agrochemical Synthesis: Building block for developing advanced herbicides, fungicides, and insecticides, leveraging the halogenated aromatic system for bioactivity.
• Ligand and Catalyst Development: Used to create specialized ligands for transition metal catalysis and organocatalysts for asymmetric synthesis.
• Polymer and Material Science: Monomer for synthesizing specialty polymers, dyes, and liquid crystals, where the fluorine and chlorine atoms impart unique electronic and physical properties.
• Chemical Research & Development: A versatile reagent in academic and industrial R&D for exploring new reaction pathways and creating compound libraries for screening.

Basic Information

Product Name	3-Chloro-2-Fluorobenzylamine
CAS No.	72235-55-3
Molecular Formula	C7H7ClFN
Molecular Weight	159.59 g/mol
Synonyms	(3-Chloro-2-fluorophenyl)methanamine; 1-(3-Chloro-2-fluorophenyl)methanamine; 2-Fluoro-3-chlorobenzylamine; Benzenemethanamine, 3-chloro-2-fluoro-; 3-Chloro-2-fluoro-benzenemethanamine; 3-Chloro-2-fluorobenzyl amine; 2-Fluoro-3-chlorobenzyl amine
EINECS	Contact for details

Quality Control

Our 3-Chloro-2-Fluorobenzylamine is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment ensures material consistency and reliability for your critical synthesis processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.