Description

2-Chloro-3-Fluoro-Benzylamine is a versatile halogenated benzylamine derivative, a key building block in advanced organic synthesis. Its molecular structure, featuring both chloro and fluoro substituents on the aromatic ring, makes it a critical intermediate for introducing specific steric and electronic properties into target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing new active ingredients.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of next-generation herbicides, fungicides, and insecticides, where the fluorine and chlorine atoms enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science: Employed in the synthesis of advanced polymers, liquid crystals, and organic electronic materials requiring specific halogenated aromatic units.
• Chemical Research & Development: A valuable scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis for high-throughput screening.

Basic Information

Product Name	2-Chloro-3-Fluoro-Benzylamine
CAS No.	72235-54-2
Molecular Formula	C7H7ClFN
Molecular Weight	159.59 g/mol
Synonyms	(2-Chloro-3-fluorophenyl)methanamine; 1-(2-Chloro-3-fluorophenyl)methanamine; 2-Chloro-3-fluorobenzylamine; Benzenemethanamine, 2-chloro-3-fluoro-; α-Amino-2-chloro-3-fluorotoluene; 2-Chloro-3-fluoro-α-toluidine; 2-Chloro-3-fluorobenzyl amine
EINECS	Contact for details

Quality Control

Our 2-Chloro-3-Fluoro-Benzylamine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring consistency and reliability for your most demanding synthesis projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product stability and performance. Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Individual Unknown Impurity	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.