Description

1-(Cyclopropylmethyl)Pyrrolidine-2-Methylamine is a specialized pyrrolidine derivative featuring a cyclopropylmethyl substituent, which imparts unique steric and electronic properties. This compound is a valuable chiral amine building block, essential for constructing complex molecular architectures in advanced pharmaceutical synthesis. It is primarily utilized by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new drug candidates, particularly for central nervous system (CNS) and antiviral therapies.
• Agrochemical Synthesis: Used as a precursor in the creation of novel pesticides and herbicides, leveraging its structural motif for biological activity.
• Ligand and Catalyst Development: Serves as a backbone for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Chemical Research: Employed in academic and industrial R&D for exploring new reaction pathways and constructing nitrogen-containing heterocycles.
• Fine Chemical Production: Acts as a building block for specialty chemicals, flavors, and fragrances requiring specific stereochemistry.

Basic Information

Product Name	1-(Cyclopropylmethyl)Pyrrolidine-2-Methylamine
CAS No.	71820-57-0
Molecular Formula	C9H18N2
Molecular Weight	154.25 g/mol
Synonyms	2-(Aminomethyl)-1-(cyclopropylmethyl)pyrrolidine; (2-Pyrrolidinylmethyl)cyclopropanemethanamine; 1-(Cyclopropylmethyl)-2-(aminomethyl)pyrrolidine; 2-(Aminomethyl)-1-(cyclopropylmethyl)azacyclopentane; CPMA (abbreviation); α-(Cyclopropylmethyl)-2-pyrrolidinemethanamine; 1-(Cyclopropylmethyl)-2-methylaminopyrrolidine (tautomer reference)
EINECS	Contact for details

Quality Control

Our 1-(Cyclopropylmethyl)Pyrrolidine-2-Methylamine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment, to ensure it meets the high standards required for research and process chemistry. Certificates of Analysis (COA) with detailed chromatographic data (HPLC/GC) are provided for every shipment, ensuring full traceability and compliance with your internal specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and purity. For long-term storage, consider using an inert atmosphere.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee (enantiomeric excess)
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.