Description

Cyclobutanecarboxamidine Hydrochloride is a high-purity organic building block and chemical intermediate of significant interest in advanced synthesis. Its unique amidine functional group and cyclobutane ring structure make it a valuable precursor for constructing complex molecular architectures. This compound is primarily sought after by research institutions and pharmaceutical companies engaged in medicinal chemistry and drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Research: Used in the synthesis of novel herbicides, fungicides, and plant growth regulators, leveraging the cyclobutane scaffold for bioactivity.
• Chemical Biology & Proteomics: Acts as a reactive handle or linker in the design of chemical probes, enzyme inhibitors, and activity-based protein profiling (ABPP) agents.
• Material Science Precursor: Employed in the research and development of advanced polymers and functional organic materials with specific thermal or optical properties.
• Academic & Contract Research: Utilized in universities and CROs (Contract Research Organizations) for methodological studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	Cyclobutanecarboxamidine Hydrochloride
CAS No.	71690-89-6
Molecular Formula	C5H11ClN2
Molecular Weight	134.61 g/mol
Synonyms	Cyclobutanecarboximidamide hydrochloride; Cyclobutanecarboxamidine HCl; Cyclobutanecarboximidamide monohydrochloride; 1-Cyclobutanecarboxamidine hydrochloride; Cyclobutanecarboxylic amidine hydrochloride; Cyclobutanecarboxamidine, hydrochloride; Amidino-cyclobutane hydrochloride
EINECS	Contact for details

Quality Control

Our Cyclobutanecarboxamidine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and development. A detailed Certificate of Analysis (COA) is provided with every shipment to guarantee traceability, consistency, and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.