Description

5-[(Trimethylsilyl)Oxy]-Pentanoicacidmethylester is a versatile organosilicon compound, specifically a silyl-protected ester derivative, valued for its role as a key synthetic intermediate and protecting group in advanced organic synthesis. Its primary commercial value lies in enabling complex multi-step reactions, particularly in the production of pharmaceuticals and fine chemicals, by offering selective reactivity and stability. This product is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to streamline synthetic routes and improve yields.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds requiring protected hydroxyl or carboxylic acid functionalities.
• Peptide Synthesis: Used as a protecting group reagent for side-chain functionalization during solid-phase or solution-phase peptide synthesis.
• Natural Product Synthesis: Facilitates the construction of complex natural product scaffolds by providing a stable, yet selectively removable, silyl ether protecting group.
• Agrochemical Research: Serves as an intermediate in the development of novel herbicides, fungicides, and plant growth regulators.
• Material Science Precursor: Can be utilized in the synthesis of silicon-containing polymers or hybrid organic-inorganic materials.
• Cross-Coupling Reactions: Acts as a substrate or reagent in various metal-catalyzed cross-coupling reactions to form new carbon-carbon bonds.

Basic Information

Product Name	5-[(Trimethylsilyl)Oxy]-Pentanoicacidmethylester
CAS No.	71541-87-2
Molecular Formula	C9H20O3Si
Molecular Weight	204.34 g/mol
Synonyms	Methyl 5-(trimethylsilyloxy)pentanoate; 5-(Trimethylsiloxy)pentanoic Acid Methyl Ester; Pentanoic acid, 5-(trimethylsilyloxy)-, methyl ester; Methyl 5-hydroxyvalerate trimethylsilyl ether; TMS-protected methyl 5-hydroxypentanoate; Methyl 5-((trimethylsilyl)oxy)valerate; 5-(Trimethylsilyloxy)valeric acid methyl ester
EINECS	Contact for details

Quality Control

Our 5-[(Trimethylsilyl)Oxy]-Pentanoicacidmethylester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including GC/HPLC for purity and identity verification, to ensure it meets precise customer specifications and industry standards. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong acids, bases, and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.